ArticleJournal of molecular and cellular cardiology2017
Conditional knockout of Fgf13 in murine hearts increases arrhythmia susceptibility and reveals novel ion channel modulatory roles.
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Article in Journal of molecular and cellular cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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35citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
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Who cites it
35 citing papers in PubMed, 58 citations in OpenAlex.
- Targeting Arrhythmogenic Late Sodium Current by FHF1Circulation research · 2026Article
- Fibroblast growth factor 13 deficiency attenuates doxorubicin-induced cardiotoxicity by regulating Parkin-mediated myocardial injury.Acta biochimica et biophysica Sinica · 2026Article
- FGF13 is not secreted from mouse neurons.JCI insight · 2026Article
- FGF13 Regulates VGSC-Independent Cardiomyocyte Impulse Propagation via Cx43 Trafficking.Circulation research · 2025Article
- The NaV1.5 auxiliary subunit FGF13 modulates channels by regulating membrane cholesterol independent of channel binding.The Journal of clinical investigation · 2025Article
- High-Fat Diet Differentially Regulates Fibroblast Growth Factor Expression in Metabolic Tissues of Young and Aged Male Mice.Journal of the Endocrine Society · 2025Article
- Loss of intracellular FGF14 (iFGF14) increases excitability of mature hippocampal pyramidal neurons.The Journal of general physiology · 2025Article
- Ceramide-induced FGF13 impairs systemic metabolic health.Cell metabolism · 2025Article
- The peripheral Atf3Acta biochimica et biophysica Sinica · 2025Article
- Interneuron FGF13 regulates seizure susceptibility via a sodium channel-independent mechanism.eLife · 2025Article
- Interneuron FGF13 regulates seizure susceptibility via a sodium channel-independent mechanism.bioRxiv : the preprint server for biology · 2024Article
- Decreased Left Atrial Cardiomyocyte Fibroblast Growth Factor 13 Expression Increases Vulnerability to Postoperative Atrial Fibrillation in Humans.Journal of the American Heart Association · 2024Article
- InducibleActa biochimica et biophysica Sinica · 2024Article
- Determinants of iFGF13-mediated regulation of myocardial voltage-gated sodium (NaV) channels in mouse.The Journal of general physiology · 2023Article
- Nr2f1a maintains atrialeLife · 2023Article
- Differential regulation of cardiac sodium channels by intracellular fibroblast growth factors.The Journal of general physiology · 2023Article
- Identification of FGF13 as a Potential Biomarker and Target for Diagnosis of Impaired Glucose Tolerance.International journal of molecular sciences · 2023Article
- FGF12 is a novel component of the nucleolar NOLC1/TCOF1 ribosome biogenesis complex.Cell communication and signaling : CCS · 2022Article
- New developments in the biology of fibroblast growth factors.WIREs mechanisms of disease · 2022Review
- FGF13 enhances resistance to platinum drugs by regulating hCTR1 and ATP7A via a microtubule-stabilizing effect.Cancer science · 2021Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 2 countries.
Xiangchong WangDepartment of Pharmacology, Hebei Medical University, Shijiazhuang 050017, China; The Key Laboratory of Neural and Vascular Biology, Ministry of Education, China, Shijiazhuang, 050017, China; The Key Laboratory of New Drug Pharmacology and Toxicology, Hebei Province, Shijiazhuang 050017, China.
He TangDepartment of Pharmacology, Hebei Medical University, Shijiazhuang 050017, China; The Key Laboratory of Neural and Vascular Biology, Ministry of Education, China, Shijiazhuang, 050017, China; The Key Laboratory of New Drug Pharmacology and Toxicology, Hebei Province, Shijiazhuang 050017, China.
Eric Q WeiIon Channel Research Unit, Department of Medicine/Cardiology and Pharmacology, Duke University Medical Center, Durham, NC 27710, USA.
Zhihua WangDepartment of Pharmacology, Hebei Medical University, Shijiazhuang 050017, China; The Key Laboratory of Neural and Vascular Biology, Ministry of Education, China, Shijiazhuang, 050017, China; The Key Laboratory of New Drug Pharmacology and Toxicology, Hebei Province, Shijiazhuang 050017, China.
Jing YangDepartment of Physiology, Hebei Medical University, Shijiazhuang 050017, China.
Rong YangDepartment of Cardiology, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, China.
Sheng WangDepartment of Physiology, Hebei Medical University, Shijiazhuang 050017, China.
Yongjian ZhangDepartment of Pharmacology, Hebei Medical University, Shijiazhuang 050017, China; The Key Laboratory of Neural and Vascular Biology, Ministry of Education, China, Shijiazhuang, 050017, China; The Key Laboratory of New Drug Pharmacology and Toxicology, Hebei Province, Shijiazhuang 050017, China.
Geoffrey S PittIon Channel Research Unit, Department of Medicine/Cardiology and Pharmacology, Duke University Medical Center, Durham, NC 27710, USA.
Hailin ZhangDepartment of Pharmacology, Hebei Medical University, Shijiazhuang 050017, China; The Key Laboratory of Neural and Vascular Biology, Ministry of Education, China, Shijiazhuang, 050017, China; The Key Laboratory of New Drug Pharmacology and Toxicology, Hebei Province, Shijiazhuang 050017, China. Electronic address: zhanghl@hebmu.edu.cn.
Chuan WangDepartment of Pharmacology, Hebei Medical University, Shijiazhuang 050017, China; The Key Laboratory of Neural and Vascular Biology, Ministry of Education, China, Shijiazhuang, 050017, China; The Key Laboratory of New Drug Pharmacology and Toxicology, Hebei Province, Shijiazhuang 050017, China. Electronic address: wangchuan@hebmu.edu.cn.
Hebei Medical University · CNMinistry of Education of the People's Republic of China · CNDuke Medical Center · USDuke University · US
Funding
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007171 · NIGMS · DUKE UNIVERSITY · PI KONTOS, CHRISTOPHER D · 1985 to 2021
$31.2MCalcium regulation and dysregulation of cardiac ion channelsR01HL071165 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI PITT, GEOFFREY S · 2002 to 2017
$5.2MStructural studies of NaV1.5 and functional implications.R01HL112918 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI PITT, GEOFFREY S · 2013 to 2016
$1.5MNHLBI NIH HHS R01 HL071165NHLBI NIH HHS R01 HL112918NIGMS NIH HHS T32 GM007171
Abstract
The intracellular fibroblast growth factors (iFGF/FHFs) bind directly to cardiac voltage gated Na
Indexed as
Genetic Predisposition to DiseaseAction PotentialsAnimalsArrhythmias, CardiacDisease Models, AnimalElectrocardiographyFemaleFibroblast Growth FactorsGene Knockout TechniquesGene TargetingGenetic LociIon ChannelsMaleMiceMice, KnockoutMyocytes, Cardiacfibroblast growth factor 13Fibroblast Growth FactorsIon ChannelsSodium ChannelsCardiac conditional knockout miceFGF13Fibroblast growth factor homologous factorsK(+) channelNa(+) channelVentricular tachyarrhythmias
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.