ArticleHealth and quality of life outcomes2017
An empirical evaluation of the SF-12, SF-6D, EQ-5D and Michigan Hand Outcome Questionnaire in patients with rheumatoid arthritis of the hand.
Article in Health and quality of life outcomes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Minimal important differences of measurement instruments used in rheumatoid arthritis: a scoping review.BMC rheumatology · 2025Pooled it
- Health-Related Quality of Life following Total Thyroidectomy and Lobectomy for Differentiated Thyroid Carcinoma: A Systematic Review.Current oncology (Toronto, Ont.) · 2022Pooled it
- Minimal important differences for improvement in shoulder condition patient-reported outcomes: a systematic review to inform aBMJ open · 2019Pooled it
- An Exercise and Educational and Self-management Program Delivered With a Smartphone App (CareHand) in Adults With Rheumatoid Arthritis of the Hands: Randomized Controlled Trial.JMIR mHealth and uHealth · 2022Trial
- When eye disease affects the mind: Psychological burden and functioning in autoimmune ophthalmology.World journal of clinical cases · 2026Article
- Observational
- Long-term sutimlimab improves quality of life for patients with cold agglutinin disease: CARDINAL 2-year follow-up.Blood advances · 2023Article
- Estimating the effects of physical violence and serious injury on health-related quality of life: Evidence from 19 waves of the Household, Income and Labour Dynamics in Australia Survey.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Article
- Assessment of Quality of Life 8-Dimension (AQoL-8D): translation, validation, and application in two Dutch trials in patients with epilepsy and schizophrenia.Expert review of pharmacoeconomics & outcomes research · 2022Article
- Predicting presenteeism using measures of health status.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Article
- The Effect of Immobilization Position on Functional Outcomes and Complications Associated With the Conservative Treatment of Distal Radius Fractures: A Systematic Review.Journal of hand surgery global online · 2022Article
- Article
- Association between knee symptoms, change in knee symptoms over 6-9 years, and SF-6D health state utility among middle-aged Australians.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Article
- A qualitative exploration of the patient experience of erosive and non-erosive hand osteoarthritis.Journal of patient-reported outcomes · 2021Article
- Article
- Associations between perceived environmental pollution and health-related quality of life in a Chinese adult population.Health and quality of life outcomes · 2020Article
- Association between disease activity measured by RAPID3 and health-related quality of life in patients with rheumatoid arthritis.Rheumatology international · 2019Article
- Site-specific Patient-reported Outcome Measures for Hand Conditions: Systematic Review of Development and Psychometric Properties.Plastic and reconstructive surgery. Global open · 2019Article
- Discriminative validity of the EQ-5D-5 L and SF-12 in older adults with arthritis.Health and quality of life outcomes · 2019Article
- A head-to-head comparison of EQ-5D-5 L and SF-6D in Chinese patients with low back pain.Health and quality of life outcomes · 2019Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundThe aim of this study was to assess the psychometric properties, namely acceptability, validity, reliability, interpretability and responsiveness of the EuroQol EQ-5D (EQ-5D visual analogue (VAS) and EQ-5D (utility)), Short Form 12 Dimensions (SF-12), SF-6D and Michigan Hand Outcome Questionnaire (MHQ) in patients with rheumatoid arthritis (RA) of the hand.
methodsThe empirical investigation was based upon data from a randomised controlled trial of 488 adults with rheumatoid arthritis who had pain and dysfunction of the hands and/or wrists. Participants completed the EQ-5D, SF-12 and MHQ at baseline and at 4 and 12 months follow up. Acceptability was measured using completion rates over time; construct validity using the "known groups" approach, based on pain troublesomeness; convergent validity using spearman's rho correlation (ρ); reliability using internal consistency (Cronbach's alpha); interpretability using minimal important differences (MID); and responsiveness using effect sizes and standardised response means (SRM) stratified by level of self-rated improvement in hand and wrist function or level of self-rated benefit and satisfaction from trial treatments.
resultsAt baseline, the study population had a mean age of 62.4 years, a mean MHQ score of 52.1 and included 76% women. The EQ-5D (utility) had the highest completion rates across time points. All instruments discriminated between pre-specified groups based on pain troublesomeness. Convergent validity analysis indicated that the MHQ score correlated strongly with the EQ-5D (ρ = 0.65) and SF-6D (ρ = 0.63) utility scores. The MHQ was most responsive at detecting change in indicators of RA pain severity between baseline and 4 months, whilst minimal important differences varied considerably across PROMs.
conclusionsThe instruments evaluated in this study displayed varying psychometric properties in the context of RA of the hand. The selection of a preferred instrument in evaluative studies should ultimately depend on the relative importance placed on individual psychometric properties and the importance placed on generation of health utilities for economic evaluation purposes.
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