Evidence map›Paper›PMID 28118369›Full record

ArticlePloS one2017

Autonomic Modulation in Duchenne Muscular Dystrophy during a Computer Task: A Prospective Control Trial.

Mayra Priscila Boscolo Alvarez, Talita Dias da Silva, Francis Meire Favero, Vitor Engrácia Valenti, Rodrigo Daminello Raimundo, Luiz Carlos Marques Vanderlei, David M Garner, Carlos Bandeira de Mello Monteiro

Open access · goldAbstract readControlled Clinical Trial
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Mayra Priscila Boscolo AlvarezPhysical Therapy, Speech and Occupational Therapy Department, School of Medicine, University of São Paulo, São Paulo, SP, Brazil.
Talita Dias da SilvaFederal University of São Paulo, Paulista School of Medicine, São Paulo, SP, Brazil.
Francis Meire FaveroFederal University of São Paulo, Department of Neurology/Neurosurgery, Paulista School of Medicine, São Paulo, SP, Brazil.ORCID http://orcid.org/0000-0001-8063-8167
Vitor Engrácia ValentiAutonomic Nervous System Center Study, Speech Therapy Department Faculty of Sciences, Paulista State University (UNESP), Marília, SP, Brazil.
Rodrigo Daminello RaimundoLaboratory Design and Scientific Writing, Department of Community Health, ABC Medical School, Santo André, SP, Brazil.
Luiz Carlos Marques VanderleiDepartment of Physiotherapy, Paulista State University (UNESP), Presidente Prudente, São Paulo, SP, Brazil.
David M GarnerCardiorespiratory Research Group, Department of Biological and Medical Sciences, Faculty of Health and Life Sciences, Oxford Brookes University, Gipsy Lane, Oxford OX3 0BP, United Kingdom.
Carlos Bandeira de Mello MonteiroPhysical Therapy, Speech and Occupational Therapy Department, School of Medicine, University of São Paulo, São Paulo, SP, Brazil.
Universidade de São Paulo · BRUniversidade Federal de São Paulo · BRFaculdade de Medicina do ABC · BROxford Brookes University · GBUniversidade Estadual Paulista (Unesp) · BRUniversidade Paulista · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDuchenne Muscular Dystrophy (DMD) is characterized by progressive muscle weakness that can lead to disability. Owing to functional difficulties faced by individuals with DMD, the use of assistive technology is essential to provide or facilitate functional abilities. In DMD, cardiac autonomic dysfunction has been reported in addition to musculoskeletal impairment. Consequently, the objective was to investigate acute cardiac autonomic responses, by Heart Rate Variability (HRV), during computer tasks in subjects with DMD.

methodHRV was assessed by linear and nonlinear methods, using the heart rate monitor Polar RS800CX chest strap Electrocardiographic measuring device. Then, 45 subjects were included in the group with DMD and 45 in the healthy Typical Development (TD) control group. They were assessed for twenty minutes at rest sitting, and five minutes after undergoing a task on the computer.

resultsIndividuals with DMD had a statistically significant lower parasympathetic cardiac modulation at rest when compared to the control group, which further declined when undergoing the tasks on the computer.

conclusionDMD patients presented decreased HRV and exhibited greater intensity of cardiac autonomic responses during computer tasks characterized by vagal withdrawal when compared to the healthy TD control subjects.

Indexed as

Adaptation, PhysiologicalAdolescentAutonomic Nervous SystemBlood PressureElectrocardiography, AmbulatoryGames, ExperimentalHeart Conduction SystemHeart RateHumansMaleMuscular Dystrophy, DuchenneProspective StudiesPsychomotor PerformanceRestStress, PsychologicalVagus Nerve

Identifiers

PMID28118369
PMCPMC5261738
OpenAlexW2581784948

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.