Trial reportThe Clinical journal of pain2017
Treatment Adherence in Child and Adolescent Chronic Migraine Patients: Results From the Cognitive-Behavioral Therapy and Amitriptyline Trial.
Trial report in The Clinical journal of pain, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 28 citations in OpenAlex.
- Investigation into the impact of technology-based motivation program applied to children following cancer diagnosis and their families: a randomized controlled study.BMC psychology · 2025Trial
- Cognitive Behavioral Therapy for Children With Headaches: Will an App Do the Trick?Journal of child neurology · 2023Trial
- Psychological interventions for migraine.Nature reviews. Neurology · 2026Review
- Behavioral therapy in migraine: Expanding the therapeutic arsenal.European journal of neurology · 2024Review
- Pharmacist-Led Discharge Transitions of Care Interventions for Pediatric Patients: A Narrative Review.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2023Article
- Breaking the cycle: unraveling the diagnostic, pathophysiological and treatment challenges of refractory migraine.Frontiers in neurology · 2023Review
- Aligning with Patients and Families: Exploring Youth and Caregiver Openness to Pediatric Headache Interventions.Children (Basel, Switzerland) · 2022Article
- The psychosocial needs of adolescent and young adult kidney transplant recipients, and associated interventions: a scoping review.BMC psychology · 2022Article
- Psychological Interventions for Pediatric Headache Disorders: A 2021 Update on Research Progress and Needs.Current pain and headache reports · 2022Review
- The Psychiatric Comorbidities of Migraine in Children and Adolescents.Current pain and headache reports · 2021Review
- Focus group findings on the migraine patient experience during research studies and ideas for future investigations.Cephalalgia : an international journal of headache · 2020Article
- Review
- Adherence to Behavioral Therapy for Migraine: Knowledge to Date, Mechanisms for Assessing Adherence, and Methods for Improving Adherence.Current pain and headache reports · 2019Review
- Features of Primary Chronic Headache in Children and Adolescents and Validity of Ichd 3 Criteria.Frontiers in neurology · 2019Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesTo examine treatment adherence among children and adolescents with chronic migraine who volunteered to be in a clinical trial using 3 measures: treatment session attendance, therapy homework completion, and preventive medication use by daily diary. MATERIALS AND
methodsAnalyses are secondary from a trial of 135 youth aged 10 to 17 years diagnosed with chronic migraine and with a Pediatric Migraine Disability Score over 20. Participants were randomly assigned to cognitive-behavioral therapy plus amitriptyline (CBT+A, N=64) or headache education plus amitriptyline (HE+A, N=71). Therapists recorded session attendance. Completion of homework/practice between sessions was reported to therapists by patients. Patients reported preventive medication adherence using a daily headache diary.
resultsMean session attendance adherence out of 10 treatment sessions was 95% for CBT+A and 99% for HE+A. CBT+A participants reported completing a mean of 90% of home practice of CBT skills between the 10 sessions. Participants reported taking amitriptyline daily at a mean level of 90% when missing diaries were excluded and 79% when missing diaries were considered as missed doses of medication. DISCUSSION: Our findings demonstrate that youth with chronic migraine who agree to be a part of a clinical trial do quite well at attending therapy sessions, and report that they are adherent to completing home/practice between sessions and taking medication. These results lend further support to consideration of CBT+A as a first-line treatment for youth with chronic migraine and suggest that measurement of adherence when this treatment is provided in practice will be important.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.