Evidence map›Paper›PMID 28117777›Full record

ArticleJournal of visualized experiments : JoVE2017

Engineering Molecular Recognition with Bio-mimetic Polymers on Single Walled Carbon Nanotubes.

Jackson T Del Bonis-O'Donnell, Abraham Beyene, Linda Chio, Gözde Demirer, Darwin Yang, Markita P Landry

Open access · bronzeAbstract readVideo-Audio Media
In one paragraph

Article in Journal of visualized experiments : JoVE, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jackson T Del Bonis-O'DonnellDepartment of Chemical and Biomolecular Engineering, University of California Berkeley.
Abraham BeyeneDepartment of Chemical and Biomolecular Engineering, University of California Berkeley.
Linda ChioDepartment of Chemical and Biomolecular Engineering, University of California Berkeley.
Gözde DemirerDepartment of Chemical and Biomolecular Engineering, University of California Berkeley.
Darwin YangDepartment of Chemical and Biomolecular Engineering, University of California Berkeley.
Markita P LandryDepartment of Chemical and Biomolecular Engineering, University of California Berkeley; California Institute for Quantitative Biosciences (QB3), University of California Berkeley; landry@berkeley.edu.
University of California, Berkeley · USQB3 · US

Funding

Single-Molecule Imaging of Biological Trauma:Cytokine-Based Intracellular CommunicationR35GM128922 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI LANDRY, MARKITA · 2019 to 2023
$2.0M
Novel optical probe for dopamine release in neural circuitsR21EY029405 · NEI · UNIVERSITY OF CALIFORNIA BERKELEY · PI FELLER, MARLA, LANDRY, MARKITA · 2018 to 2019
$428k
NEI NIH HHS R21 EY029405NIGMS NIH HHS R35 GM128922
6 · The paper itself

Abstract

Semiconducting single-wall carbon nanotubes (SWNTs) are a class of optically active nanomaterial that fluoresce in the near infrared, coinciding with the optical window where biological samples are most transparent. Here, we outline techniques to adsorb amphiphilic polymers and polynucleic acids onto the surface of SWNTs to engineer their corona phases and create novel molecular sensors for small molecules and proteins. These functionalized SWNT sensors are both biocompatible and stable. Polymers are adsorbed onto the nanotube surface either by direct sonication of SWNTs and polymer or by suspending SWNTs using a surfactant followed by dialysis with polymer. The fluorescence emission, stability, and response of these sensors to target analytes are confirmed using absorbance and near-infrared fluorescence spectroscopy. Furthermore, we demonstrate surface immobilization of the sensors onto glass slides to enable single-molecule fluorescence microscopy to characterize polymer adsorption and analyte binding kinetics.

Indexed as

AdsorptionBiomimetic MaterialsNanotubes, CarbonPolymersSonicationSpectroscopy, Near-InfraredSurface-Active AgentsNanotubes, CarbonPolymersSurface-Active Agents

Identifiers

PMID28117777
PMCPMC5408597
OpenAlexW2569014999

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.