ReviewInternational journal of molecular sciences2017
What Do We Know about Opioids and the Kidney?
Review in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 97 citations in OpenAlex.
- Retrospective Metabolomics Profiling of Clinical Urine Drug Screen Samples Reveals Features Associated with Opiate Exposure.Metabolites · 2026Article
- Endurance training mitigates morphine-induced renal dysfunction in young and aged rats: involvement of oxidative stress, SIRT1, Klotho and TFAM.Biogerontology · 2026Article
- Impact of sedation with propofol and/or sufentanil on short-term outcomes in patients admitted to the intensive care unit: A retrospective study.The Journal of international medical research · 2026Article
- Protective effect of linalool against morphine-induced renal injury: Modulation of oxidative stress and PI3K/AKT/L-FABP signaling pathway.Iranian journal of basic medical sciences · 2026Article
- Giant Bladder Calculus Presenting as A Rare Cause of Renal Impairment in A Young Adult with Substance Use Disorder.European journal of case reports in internal medicine · 2026Article
- Incidence and risk factors for postoperative urinary retention in older patients with hip fracture: a scoping review.BMJ open · 2025Article
- Potential Drug Dose-Specific Adverse Three-Drug Combinations: A US Insurance Claims Data-Based Study.Pharmacoepidemiology and drug safety · 2025Article
- Renal Implications of Kappa Opioid Receptor Signaling in Sprague-Dawley Rats.Function (Oxford, England) · 2025Article
- Article
- The association between hot days and substance-related suicides: a time-stratified case-crossover analysis in British Columbia, Canada.Environmental health : a global access science source · 2025Article
- Opioid use and poisoning in hospitalized patients with chronic kidney disease.Journal of nephrology · 2025Article
- The emerging role of anoctamin-1 in cardiac and cerebrovascular diseases.Frontiers in cardiovascular medicine · 2025Review
- Tackling new psychoactive substances through metabolomics: UHPLC-HRMS study on natural and synthetic opioids in male and female murine models.Scientific reports · 2024Article
- Assessing the Impact of Morphine on Adverse Outcomes in ACS Patients Treated with P2Y12 Inhibitors: Insights from Multiple Real-World Evidence.Drug design, development and therapy · 2024Article
- Could chronic opioid use be an additional risk of hepatic damage in patients with previous liver diseases, and what is the role of microbiome?Frontiers in microbiology · 2024Review
- Risk of Hospital-Acquired Acute Kidney Injury among Adult Opioid Analgesic Users: A Multicenter Real-World Data Analysis.Kidney diseases (Basel, Switzerland) · 2023Article
- Acute kidney injury associated with nephrotoxic drugs in critically ill patients: a multicenter cohort study using electronic health record data.Clinical kidney journal · 2023Article
- Using machine learning to predict adverse events in acute coronary syndrome: A retrospective study.Clinical cardiology · 2023Article
- Cannabis Use and Risk of Acute Kidney Injury in Patients with Advanced Chronic Kidney Disease Transitioning to Dialysis.Cannabis and cannabinoid research · 2023Observational
- Uncontrolled pain in critically ill patients and acute kidney injury: a hypothesis-generating cohort study.BMC nephrology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Evidence suggests a link between opioid use and kidney disease. This review summarizes the known renal manifestations of opioid use including its role in acute and chronic kidney injury. Both the direct and indirect effects of the drug, and the context which leads to the development of renal failure, are explored. While commonly used safely for pain control and anesthesia in those with kidney disease, the concerns with respect to side effects and toxicity of opioids are addressed. This is especially relevant with the worldwide increase in the use of opioids for medical and recreational use.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.