Evidence map›Paper›PMID 28117662›Full record

ArticleeLife2017

Multivariate cross-frequency coupling via generalized eigendecomposition.

Michael X Cohen

Abstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Time, space, memory and brain-body rhythms.Nature reviews. Neuroscience · 2026
    Review
  3. Article
  4. Article
  5. Cross-Frequency Coupling as a Biomarker for Early Stroke Recovery.Neurorehabilitation and neural repair · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Midfrontal theta dynamics index the monitoring of postural stability.Cerebral cortex (New York, N.Y. : 1991) · 2023
    Article
  10. Article
  11. Review
  12. Multitaper estimates of phase-amplitude coupling.Journal of neural engineering · 2021
    Article
  13. Article
  14. Multivariate Analysis of Bivariate Phase-Amplitude Coupling in EEG Data Using Tensor Robust PCA.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2021
    Article
  15. Article
  16. Multiple Midfrontal Thetas Revealed by Source Separation of Simultaneous MEG and EEG.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Michael X CohenDonders Center for Neuroscience, Radboud University Nijmegen Medical Centre, Radboud University, Nijmegen, Netherlands.ORCID 0000-0002-1879-3593

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper presents a new framework for analyzing cross-frequency coupling in multichannel electrophysiological recordings. The generalized eigendecomposition-based cross-frequency coupling framework (gedCFC) is inspired by source-separation algorithms combined with dynamics of mesoscopic neurophysiological processes. It is unaffected by factors that confound traditional CFC methods-such as non-stationarities, non-sinusoidality, and non-uniform phase angle distributions-attractive properties considering that brain activity is neither stationary nor perfectly sinusoidal. The gedCFC framework opens new opportunities for conceptualizing CFC as network interactions with diverse spatial/topographical distributions. Five specific methods within the gedCFC framework are detailed, these are validated in simulated data and applied in several empirical datasets. gedCFC accurately recovers physiologically plausible CFC patterns embedded in noise that causes traditional CFC methods to perform poorly. The paper also demonstrates that spike-field coherence in multichannel local field potential data can be analyzed using the gedCFC framework, which provides significant advantages over traditional spike-field coherence analyses. Null-hypothesis testing is also discussed.

Indexed as

Action PotentialsBrain WavesModels, NeurologicalBiostatisticsBrainElectroencephalographyNerve Netcross-frequency couplingdimensionality reductionhumanmouseneural oscillationsneuroscienceratrhesus macaquesource separationspike-field coherence

Identifiers

PMID28117662
PMCPMC5262375

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.