Evidence map›Paper›PMID 28117597›Full record

ArticleAIDS research and human retroviruses2017

Amino Acid Concentrations in HIV-Infected Youth Compared to Healthy Controls and Associations with CD4 Counts and Inflammation.

Thomas R Ziegler, Suzanne E Judd, Joshua H Ruff, Grace A McComsey, Allison Ross Eckard

Abstract read
In one paragraph

Article in AIDS research and human retroviruses, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Metabolomics of HIV in the Modern cART Era.Advances in experimental medicine and biology · 2026
    Review
  4. Article
  5. Health-Related Physical Fitness Evaluation in HIV-Diagnosed Children and Adolescents: A Scoping Review.International journal of environmental research and public health · 2024
    Article
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Thomas R Ziegler1 Department of Medicine, Emory University School of Medicine , Atlanta, Georgia .
Suzanne E Judd2 Department of Biostatistics, University of Alabama at Birmingham , Birmingham, Alabama.
Joshua H Ruff3 Rush Medical College , Chicago, Illinois.
Grace A McComsey4 Department of Pediatrics for Case, Rainbow Babies & Children's Hospital, Case Western Reserve University/Case Medical Center , Cleveland, Ohio.
Allison Ross Eckard5 Departments of Pediatrics and Medicine, Divisions of Infectious Diseases, Medical University of South Carolina , Charleston, South Carolina.
Emory University · USRush University Medical Center · USUniversity of Alabama at Birmingham · US

Funding

Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Ann M Chahroudi, Colleen F Kelley · 2002 to 2026
$74.0M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
Vitamin D, drug metabolism, and cardiovascular complications in pediatric HIVR01HD070490 · NICHD · CASE WESTERN RESERVE UNIVERSITY · PI MCCOMSEY, GRACE A · 2011 to 2015
$1.7M
Patient Oriented Research In Clinical NutritionK24DK096574 · NIDDK · EMORY UNIVERSITY · PI ZIEGLER, THOMAS R · 2012 to 2016
$888k
Vitamin D status and HIV-related complications in children and young adultsK23HD069199 · NICHD · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI ECKARD, ALLISON ROSS · 2012 to 2016
$631k
NCATS NIH HHS UL1 TR000454NIAID NIH HHS P30 AI050409NICHD NIH HHS K23 HD069199NICHD NIH HHS R01 HD070490NIDDK NIH HHS K24 DK096574
6 · The paper itself

Abstract

Amino acids play critical roles in metabolism, cell function, body composition and immunity, but little data on plasma amino acid concentrations in HIV are available. We evaluated plasma amino acid concentrations and associations with CD4 counts and inflammatory biomarkers in HIV-infected youth. HIV-infected subjects with a high (≥500 cells/mm

Indexed as

AdolescentAdultAmino AcidsCD4 Lymphocyte CountChildChild, PreschoolCytokinesFemaleHIV InfectionsHumansInfantInflammationMaleYoung AdultAmino AcidsCytokinesamino acidsCD4 countHIVpediatrics

Identifiers

PMID28117597
PMCPMC5512337
OpenAlexW2977620071

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.