Evidence map›Paper›PMID 28117457›Full record

ArticleScientific reports2017

The aliphatic amidase AmiE is involved in regulation of Pseudomonas aeruginosa virulence.

Thomas Clamens, Thibaut Rosay, Alexandre Crépin, Teddy Grandjean, Takfarinas Kentache, Julie Hardouin, Perrine Bortolotti, Anke Neidig, Marlies Mooij, Mélanie Hillion and 11 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Insights on pathoadaptation of sequentialMicrobiology spectrum · 2025
    Article
  6. Review
  7. Exploring aggregation genes in aJournal of bacteriology · 2025
    Article
  8. Scopoletin and Scoparone fromInfection and drug resistance · 2025
    Article
  9. An insight on the powerful of bacterial quorum sensing inhibition.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Review
  10. Article
  11. Detoxification Response ofMicroorganisms · 2022
    Article
  12. Gaseous NOScientific reports · 2022
    Article
  13. Article
  14. Pseudomonas aeruginosa Biofilm Dispersion by the Human Atrial Natriuretic Peptide.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 9 institutions in 4 countries.

Thomas ClamensLaboratory of Microbiology Signals and Microenvironment LMSM EA 4312, Normandie Univ, UNIROUEN, Evreux, France.
Thibaut RosayLaboratory of Microbiology Signals and Microenvironment LMSM EA 4312, Normandie Univ, UNIROUEN, Evreux, France.
Alexandre CrépinUniv. Bretagne-Sud, EA 3884, LBCM, IUEM, Lorient, France.
Teddy GrandjeanUniv. Lille, CHU Lille, EA 7366 - Recherche Translationnelle: relations hôte pathogènes, Lille, France.
Takfarinas KentacheLaboratory « Polymères, Biopolymères, Surfaces » (UMR 6270 CNRS), Proteomic Platform PISSARO, Normandie Univ, UNIROUEN, Mont-Saint-Aignan, France.
Julie HardouinLaboratory « Polymères, Biopolymères, Surfaces » (UMR 6270 CNRS), Proteomic Platform PISSARO, Normandie Univ, UNIROUEN, Mont-Saint-Aignan, France.
Perrine BortolottiUniv. Lille, CHU Lille, EA 7366 - Recherche Translationnelle: relations hôte pathogènes, Lille, France.
Anke NeidigKarlsruhe Institute of Technology (KIT), Institute of Functional Interfaces, PO Box 3640, Karlsruhe, Germany.
Marlies MooijBIOMERIT Research Centre, University College Cork, Cork, Ireland.
Mélanie HillionLaboratory of Microbiology Signals and Microenvironment LMSM EA 4312, Normandie Univ, UNIROUEN, Evreux, France.
Julien VieillardNormandie Univ, UNIROUEN, INSA Rouen, CNRS, COBRA (UMR 6014), Evreux, France.
Pascal CosetteLaboratory « Polymères, Biopolymères, Surfaces » (UMR 6270 CNRS), Proteomic Platform PISSARO, Normandie Univ, UNIROUEN, Mont-Saint-Aignan, France.
Joerg OverhageKarlsruhe Institute of Technology (KIT), Institute of Functional Interfaces, PO Box 3640, Karlsruhe, Germany.
Fergal O'GaraBIOMERIT Research Centre, University College Cork, Cork, Ireland.
Emeline BouffartiguesLaboratory of Microbiology Signals and Microenvironment LMSM EA 4312, Normandie Univ, UNIROUEN, Evreux, France.
Alain DufourUniv. Bretagne-Sud, EA 3884, LBCM, IUEM, Lorient, France.
Sylvie ChevalierLaboratory of Microbiology Signals and Microenvironment LMSM EA 4312, Normandie Univ, UNIROUEN, Evreux, France.
Benoit GueryUniv. Lille, CHU Lille, EA 7366 - Recherche Translationnelle: relations hôte pathogènes, Lille, France.
Pierre CornelisLaboratory of Microbiology Signals and Microenvironment LMSM EA 4312, Normandie Univ, UNIROUEN, Evreux, France.
Marc G J FeuilloleyLaboratory of Microbiology Signals and Microenvironment LMSM EA 4312, Normandie Univ, UNIROUEN, Evreux, France.
Olivier LesouhaitierLaboratory of Microbiology Signals and Microenvironment LMSM EA 4312, Normandie Univ, UNIROUEN, Evreux, France.
Normandie Université · FRCentre Hospitalier Universitaire de Lille · FRCentre National de la Recherche Scientifique · FRKarlsruhe Institute of Technology · DEUniversity College Cork · IEInstitut National des Sciences Appliquées Rouen Normandie · FRInstitut Universitaire Européen de la Mer · FRUniversité de Bretagne Sud · FRUniversité de Lille · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have previously shown that the eukaryotic C-type natriuretic peptide hormone (CNP) regulates Pseudomonas aeruginosa virulence and biofilm formation after binding on the AmiC sensor, triggering the amiE transcription. Herein, the involvement of the aliphatic amidase AmiE in P. aeruginosa virulence regulation has been investigated. The proteome analysis of an AmiE over-producing strain (AmiE

Indexed as

Virulence FactorsAmidohydrolasesAnimalsBiofilmsCaenorhabditis elegansDictyosteliumFemaleLungMaleMice, Inbred C57BLProteomePseudomonas aeruginosaPseudomonas InfectionsQuorum SensingVirulenceamidaseAmidohydrolasesProteomeVirulence Factors

Identifiers

PMID28117457
PMCPMC5259723
OpenAlexW2582645842

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.