Evidence map›Paper›PMID 28117410›Full record

ArticleScientific reports2017

The green microalga Tetraselmis suecica reduces oxidative stress and induces repairing mechanisms in human cells.

Clementina Sansone, Christian Galasso, Ida Orefice, Genoveffa Nuzzo, Elvira Luongo, Adele Cutignano, Giovanna Romano, Christophe Brunet, Angelo Fontana, Francesco Esposito and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 133 citations in OpenAlex.

  1. Molecules (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Clementina SansoneIntegrative Marine Ecology Department, Stazione Zoologica Anton Dohrn, Villa Comunale, Naples 80121, Italy.
Christian GalassoIntegrative Marine Ecology Department, Stazione Zoologica Anton Dohrn, Villa Comunale, Naples 80121, Italy.
Ida OreficeIntegrative Marine Ecology Department, Stazione Zoologica Anton Dohrn, Villa Comunale, Naples 80121, Italy.
Genoveffa NuzzoBio-Organic Chemistry Unit, Institute of Biomolecular Chemistry-CNR, Via Campi Flegrei 34, Pozzuoli, Naples 80078, Italy.
Elvira LuongoBio-Organic Chemistry Unit, Institute of Biomolecular Chemistry-CNR, Via Campi Flegrei 34, Pozzuoli, Naples 80078, Italy.
Adele CutignanoBio-Organic Chemistry Unit, Institute of Biomolecular Chemistry-CNR, Via Campi Flegrei 34, Pozzuoli, Naples 80078, Italy.
Giovanna RomanoIntegrative Marine Ecology Department, Stazione Zoologica Anton Dohrn, Villa Comunale, Naples 80121, Italy.
Christophe BrunetIntegrative Marine Ecology Department, Stazione Zoologica Anton Dohrn, Villa Comunale, Naples 80121, Italy.
Angelo FontanaBio-Organic Chemistry Unit, Institute of Biomolecular Chemistry-CNR, Via Campi Flegrei 34, Pozzuoli, Naples 80078, Italy.
Francesco EspositoIntegrative Marine Ecology Department, Stazione Zoologica Anton Dohrn, Villa Comunale, Naples 80121, Italy.
Adrianna IanoraIntegrative Marine Ecology Department, Stazione Zoologica Anton Dohrn, Villa Comunale, Naples 80121, Italy.
Stazione Zoologica Anton Dohrn · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Green microalgae contain many active pigments such as carotenoids having antioxidant and protective activity on human cells. Here we investigate the biological activity of an ethanol/water extract of the marine green microalga Tetraselmis suecica containing high levels of carotenoids such as the xanthophylls lutein, violaxanthin, neoxanthin, antheraxanthin and loroxanthin esters. This extract has a strong antioxidant and repairing activity in the human lung cancer cell line (A549) as shown by the increased expression of dehydrocholesterol reductase-24 (DHCR24) and prostaglandin reductase 1 (PTGR1) genes and proteins. The extract also reduces prostaglandin E

Indexed as

Oxidative StressAntioxidantsCarotenoidsCell Line, TumorChlorophytaEpidermisHumansHydrogen PeroxideMicroalgaePigments, BiologicalAntioxidantsCarotenoidsHydrogen PeroxidePigments, Biological

Identifiers

PMID28117410
PMCPMC5259714
OpenAlexW2580331772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.