ArticleEndocrinology and metabolism (Seoul, Korea)2017
Thyroid Stimulating Hormone Reference Range and Prevalence of Thyroid Dysfunction in the Korean Population: Korea National Health and Nutrition Examination Survey 2013 to 2015.
Article in Endocrinology and metabolism (Seoul, Korea), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 68 papers, 1 of them a synthesis that pooled it.
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Who cites it
68 citing papers in PubMed, 1 synthesis or guideline pooled it, 103 citations in OpenAlex.
- Thyroid-stimulating hormone levels in the normal range and incident type 2 diabetes mellitus.Acta diabetologica · 2019Pooled it
- Patterns of complementary and alternative medicine use and factors influencing its utilization in thyroid cancer: findings from the MASTER study.BMC complementary medicine and therapies · 2026Trial
- Age-specific TSH reference limits and early levothyroxine effects in postmenopausal women with subclinical hypothyroidism: a prospective cohort study in Vietnam.BMC endocrine disorders · 2026Article
- Association between thyroid function and 10-year cardiovascular disease risk of patients with diabetes: a cross-sectional study using KNHANES 2013-2014.Journal of Yeungnam medical science · 2026Article
- Lifetime Atopic Dermatitis is Associated With Risk of Autoimmune Thyroid Disease: Evidence From a Nationwide Study.Allergy, asthma & immunology research · 2026Article
- Iodine Intake and Risk of Mortality: Evidence from a Nationally Representative Korean Cohort.Nutrients · 2025Article
- Investigating Birth and Thyroid Outcomes of Maternal-Fetal Environmental Exposures (IBM-E): A Cohort Protocol for Dietary Iodine and Endocrine Disruptors.Endocrinology and metabolism (Seoul, Korea) · 2025Observational
- Association of high-normal thyroid-stimulating hormone levels with metabolic syndrome and abdominal obesity in euthyroid adolescents: insights from the Korea National Health and Nutrition Examination Survey.Annals of pediatric endocrinology & metabolism · 2025Article
- Prevalence of Subclinical Hypothyroidism in Information Technology Professionals With High Screen Exposure.Cureus · 2025Article
- Low Thyrotropin Levels Are Associated With an Increased Risk of Atherosclerotic Cardiovascular Disease in Euthyroid Individuals: The Korea National Health and Nutrition Examination Survey 2013-2015.Journal of lipid and atherosclerosis · 2025Article
- Article
- Clinical Implications of Different Thyroid-Stimulating Hormone (TSH) Reference Intervals between TSH Kits for the Management of Subclinical Hypothyroidism.Endocrinology and metabolism (Seoul, Korea) · 2024Article
- Deciphering the roles of triiodothyronine (T3) and thyroid-stimulating hormone (TSH) on cardiac electrical remodeling in clinical and experimental hypothyroidism.Journal of physiology and biochemistry · 2024Review
- Management of Subclinical Hypothyroidism: A Focus on Proven Health Effects in the 2023 Korean Thyroid Association Guidelines.Endocrinology and metabolism (Seoul, Korea) · 2023Article
- The Current Status of Hyperthyroidism in Korea.Endocrinology and metabolism (Seoul, Korea) · 2023Article
- Subclinical thyroid dysfunction and chronic kidney disease: a nationwide population-based study.BMC nephrology · 2023Article
- Association between shift work and the risk of hypothyroidism in adult male workers in Korea: a cohort study.Annals of occupational and environmental medicine · 2023Article
- Association of free thyroxine with obstructive lung pattern in euthyroid middle-aged subjects: A population-based study.PloS one · 2022Article
- Comparison of Five Different Criteria for Diagnosis of Subclinical Hypothyroidism in a Large-Scale Chinese Population.Frontiers in endocrinology · 2022Article
- Thyroid Stimulating Hormone, T3 and T4 Population-based Reference Range and Children Prevalence of Thyroid Dysfunction: First Report from South of Iran.Iranian journal of pathology · 2022Article
8 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
12 authors at 6 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNo nationwide epidemiological study evaluating the prevalence of subclinical and overt forms of hypothyroidism and hyperthyroidism has yet been conducted in Korea. This study aimed to evaluate the reference range of serum thyroid stimulating hormone (TSH) and the national prevalence of thyroid dysfunctions in Korea.
methodsNation-wide cross-sectional data were analyzed from a representative sample of the civilian, non-institutionalized Korean population (n=6,564) who underwent blood testing for thyroid function and anti-thyroid peroxidase antibody (TPOAb) as part of the Korea National Health and Nutrition Examination Survey VI (2013 to 2015).
resultsThe reference interval of serum TSH in the Korean reference population was 0.62 to 6.68 mIU/L. Based on this reference interval, the prevalence of overt and subclinical hypothyroidism was 0.73% (males 0.40%, females 1.10%) and 3.10% (males 2.26%, females 4.04%), respectively. The prevalence of hypothyroidism increased with age until the age group between 50 to 59 years. Positive TPOAb were found in 7.30% of subjects (males 4.33%, females 10.62%). The prevalence of overt and subclinical hypothyroidism TPOAb-positive subjects was 5.16% and 10.88%, respectively. The prevalence of overt and subclinical hyperthyroidism was 0.54% (males 0.30%, females 0.81%) and 2.98% (males 2.43%, females, 3.59%), respectively.
conclusionThe Serum TSH reference levels in the Korean population were higher than the corresponding levels in Western countries. Differences were found in the prevalence of hypothyroidism and hyperthyroidism according to age, sex, and TPOAb positivity. This study provides important baseline information for understanding patterns of thyroid dysfunction and diseases in Korea.
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