ArticleNeurogastroenterology and motility2017
Brain networks associated with cognitive and hedonic responses to a meal.
Article in Neurogastroenterology and motility, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Conditioning by a Previous Experience Impairs the Rewarding Value of a Comfort Meal.Nutrients · 2023Trial
- Differential Effects of Western and Mediterranean-Type Diets on Gut Microbiota: A Metagenomics and Metabolomics Approach.Nutrients · 2021Trial
- Meal Enjoyment and Tolerance in Women and Men.Nutrients · 2019Trial
- Intranasal insulin enhances brain functional connectivity mediating the relationship between adiposity and subjective feeling of hunger.Scientific reports · 2017Trial
- Gastrointestinal Contributions to the Postprandial Experience.Nutrients · 2021Review
- Sex Differences and Commonalities in the Impact of a Palatable Meal on Thalamic and Insular Connectivity.Nutrients · 2020Article
- Food, Eating, and the Gastrointestinal Tract.Nutrients · 2020Review
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
backgroundWe recently reported interrelated digestive, cognitive, and hedonic responses to a meal. The aim of this study was to identify brain networks related to the hedonic response to eating.
methodsThirty-eight healthy subjects (20-38 age range) were evaluated after a 5-hour fast and after ingestion of a test meal (juice and warm ham and cheese sandwich, 300 mL, 425 kcal). Perceptual and affective responses (satiety, abdominal fullness, digestive well-being, and positive mood), and resting scans of the brain using functional MRI (3T Trio, Siemens, Germany) were evaluated immediately before and after the test meal. A high-order group independent component analysis was performed to investigate ingestion-related changes in the intrinsic connectivity of brain networks, with a focus on thalamic and insular networks. KEY
resultsIngestion induced satiation (3.3±0.4 score increase; P<.001) and abdominal fullness (2.4±0.3 score increase; P<.001). These sensations included an affective dimension involving digestive well-being (2.8±0.3 score increase; P<.001) and positive mood (1.8±0.2 score increase; P<.001). In general, thalamo-cortical connectivity increased with meal ingestion while insular-cortical connectivity mainly decreased. Furthermore, larger meal-induced changes (increase/decrease) in specific thalamic connections were associated with smaller changes in satiety/fullness. In contrast, a larger meal-induced decrease in insular-anterior cingulate cortex connectivity was associated with increased satiety, fullness, and digestive well-being. CONCLUSIONS AND INFERENCES: Perceptual and emotional responses to food intake are related to brain connectivity in defined functional networks. Brain imaging may provide objective biomarkers of subjective effects of meal ingestion.
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