ArticleEnvironmental and molecular mutagenesis2017
A longitudinal study of atrazine and 2,4-D exposure and oxidative stress markers among iowa corn farmers.
Article in Environmental and molecular mutagenesis, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 61 citations in OpenAlex.
- Shared Plant-human Biology: Herbicide Effects and New Biomarkers Perspectives.Current environmental health reports · 2026Review
- Modulating effect of glutathione (GSH) on 2,4-dichlorophenoxyacetic acid (2,4-D) toxicity.Scientific reports · 2025Article
- Occupational health complaints and demographic features of farmers exposed to agrochemicals during agricultural activity.BMC public health · 2025Article
- Microorganism-Driven 2,4-D Biodegradation: Current Status and Emerging Opportunities.Molecules (Basel, Switzerland) · 2024Review
- Exposure to Pesticides and Breast Cancer in an Agricultural Region in Brazil.Environmental science & technology · 2024Article
- An Updated Evaluation of Atrazine-Cancer Incidence Associations among Pesticide Applicators in the Agricultural Health Study Cohort.Environmental health perspectives · 2024Article
- Research Recommendations for Selected IARC-Classified Agents: Impact and Lessons Learned.Environmental health perspectives · 2023Review
- Glyphosate exposure and urinary oxidative stress biomarkers in the Agricultural Health Study.Journal of the National Cancer Institute · 2023Article
- Exposure to pesticides and oxidative stress in Brazilian agricultural communities.Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals · 2021Article
- Fabrication of gelatin microspheres containing ammonium hydrogen carbonate for the tunable release of herbicide.Biotechnology letters · 2021Article
- Pesticide use and kidney function among farmers in the Biomarkers of Exposure and Effect in Agriculture study.Environmental research · 2021Article
- Exposures to 2,4-Dichlorophenoxyacetic acid with or without endotoxin upregulate small cell lung cancer pathway.Journal of occupational medicine and toxicology (London, England) · 2021Article
- Herbicides based on 2,4-D: its behavior in agricultural environments and microbial biodegradation aspects. A review.Environmental science and pollution research international · 2020Review
- Urinary organophosphate metabolites and oxidative stress in children living in agricultural and urban communities.Environmental science and pollution research international · 2020Article
- The Enhanced and Tunable Sustained Release of Pesticides Using Activated Carbon as a Carrier.Materials (Basel, Switzerland) · 2019Article
- Temporal variability in urinary pesticide concentrations in repeated-spot and first-morning-void samples and its association with oxidative stress in healthy individuals.Environment international · 2019Article
- Levels of Urinary Biomarkers of Oxidatively Generated Damage to DNA and RNA in Different Groups of Workers Compared to General Population.International journal of environmental research and public health · 2019Article
- A longitudinal follow-up study of oxidative stress and DNA damage among farmers exposed to pesticide mixtures.Environmental science and pollution research international · 2019Article
Corrections and comments
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Authors and funding
10 authors at 8 institutions in 4 countries.
Funding
Abstract
Reactive oxygen species, potentially formed through environmental exposures, can overwhelm an organism's antioxidant capabilities resulting in oxidative stress. Long-term oxidative stress is linked with chronic diseases. Pesticide exposures have been shown to cause oxidative stress in vivo. We utilized a longitudinal study of corn farmers and non-farming controls in Iowa to examine the impact of exposure to the widely used herbicides atrazine and 2,4-dichlorophenoxyacetic acid (2,4-D) on markers of oxidative stress. 225 urine samples were collected during five agricultural time periods (pre-planting, planting, growing, harvest, off-season) for 30 farmers who applied pesticides occupationally and 10 controls who did not; all were non-smoking men ages 40-60. Atrazine mercapturate (atrazine metabolite), 2,4-D, and oxidative stress markers (malondialdehyde [MDA], 8-hydroxy-2'-deoxyguanosine [8-OHdG], and 8-isoprostaglandin-F
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.