Evidence map›Paper›PMID 28116486›Full record

ArticleHeart and vessels2017

Inferior vena cava diameter in acute decompensated heart failure as predictor of all-cause mortality.

Alexander Jobs, Kerstin Brünjes, Alexander Katalinic, Valentin Babaev, Steffen Desch, Michael Reppel, Holger Thiele

Abstract read
PubMed Publisher
In one paragraph

Article in Heart and vessels, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 39 citations in OpenAlex.

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  11. Lack of correlation between different congestion markers in acute decompensated heart failure.Clinical research in cardiology : official journal of the German Cardiac Society · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Alexander JobsDepartment of Cardiology, Angiology and Intensive Care Medicine, Medical Clinic II, University Heart Center Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Germany. alexander.jobs@uksh.de.
Kerstin BrünjesDepartment of Cardiology, Angiology and Intensive Care Medicine, Medical Clinic II, University Heart Center Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Germany.
Alexander KatalinicInsitute for Cancer Epidemiology e.V., University of Lübeck, Lübeck, Germany.
Valentin BabaevInsitute for Cancer Epidemiology e.V., University of Lübeck, Lübeck, Germany.
Steffen DeschDepartment of Cardiology, Angiology and Intensive Care Medicine, Medical Clinic II, University Heart Center Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Germany.
Michael ReppelDepartment of Cardiology, Angiology and Intensive Care Medicine, Medical Clinic II, University Heart Center Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Germany.
Holger ThieleDepartment of Cardiology, Angiology and Intensive Care Medicine, Medical Clinic II, University Heart Center Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Germany.
University of Lübeck · DEGerman Centre for Cardiovascular Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inferior vena cava (IVC) diameter can be used to approximate right atrial pressure in patients admitted for acute decompensated heart failure (ADHF). Recent studies linked IVC dilation to an increased risk of early re-admission and short-term mortality. Moreover, renal insufficiency (RI) is an established risk factor for mortality in ADHF and is associated with congestion. We hypothesized that the IVC diameter is a marker of all-cause mortality but its prognostic impact may be influenced by kidney function. We analyzed data of 1101 patients admitted for ADHF with available echocardiography of the IVC by chart review and death registry linkage. Patients were dichotomized according to a cut-off value of 21 mm. Cox proportional hazards model was used to identify mortality predictors. A dilated IVC was detected in 474 (43.1%) patients. Overall, 400 (36.3%) patients died within 3 years. All-cause mortality was significantly higher in patients with dilated IVC [hazard ratio 1.45 (confidence interval 1.21-1.74); p < 0.001]. However, a dilated IVC was only associated with all-cause mortality in patients with RI function [hazard ratio 1.60 (confidence interval 1.26-2.03); p < 0.001] but not in patients with a preserved kidney function [hazard ratio 1.04 (confidence interval 0.72-1.50); P = 0.84]. IVC diameter was identified as an independent predictor for all-cause mortality in a Cox proportional hazards model with a significant interaction between IVC diameter and baseline kidney function. In conclusion, IVC dilation is a marker of high mortality risk in patients admitted for ADHF. However, this observation was confined to patients with RI.

Indexed as

MortalityAgedAged, 80 and overBiomarkersEchocardiographyFemaleGermanyGlomerular Filtration RateHeart FailureHospitalizationHumansMaleMultivariate AnalysisPrognosisRenal InsufficiencyRisk FactorsBiomarkersAcute decompensated heart failureCongestionHeart failureInferior vena cavaPrognosisRenal insufficiency

Identifiers

PMID28116486
OpenAlexW2580593806

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.