Evidence map›Paper›PMID 28115854›Full record

ArticleOncoTargets and therapy2017

Multivoxel magnetic resonance spectroscopy identifies enriched foci of cancer stem-like cells in high-grade gliomas.

Tao He, Tianming Qiu, Xiaodong Wang, Hongxing Gui, Xilong Wang, Qikuan Hu, Hechun Xia, Gaoyang Qi, Jinsong Wu, Hui Ma

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in OncoTargets and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. MultivoxelTomography (Ann Arbor, Mich.) · 2018
    Article
  3. The biology and mathematical modelling of glioma invasion: a review.Journal of the Royal Society, Interface · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Tao HeClinical Medicine College, Ningxia Medical University; Department of Neurosurgery, General Hospital of Ningxia Medical University; Ningxia Key Laboratory of Cerebrocranial Diseases, The National Key Laboratory Incubation Base, Yinchuan.
Tianming QiuDepartment of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai.
Xiaodong WangDepartment of Radiology, General Hospital of Ningxia Medical University, Yinchuan, People's Republic of China.
Hongxing GuiDepartment of Neuroscience and Cell Biology, Robert Wood Johnson Medical School of Rutgers University, Piscataway, NJ, USA.
Xilong WangDepartment of Neurosurgery, General Hospital of Ningxia Medical University.
Qikuan HuNingxia Key Laboratory of Cerebrocranial Diseases, The National Key Laboratory Incubation Base, Yinchuan; Department of Physiology, Ningxia Medical University, Yinchuan, People's Republic of China.
Hechun XiaDepartment of Neurosurgery, General Hospital of Ningxia Medical University.
Gaoyang QiClinical Medicine College, Ningxia Medical University; Department of Neurosurgery, General Hospital of Ningxia Medical University.
Jinsong WuDepartment of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai.
Hui MaDepartment of Neurosurgery, General Hospital of Ningxia Medical University.
Ningxia Medical University · CNHuashan Hospital · CNNingxia Medical University General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study investigated the correlation between choline/creatine (Cho/Cr) ratios determined by multivoxel proton magnetic resonance spectroscopy ( PATIENTS AND

methodsSixteen patients with high-grade gliomas were recruited and underwent

resultsThe mean neurosphere formation rate in tissues with high Cho/Cr ratios was significantly increased compared with that in low Cho/Cr ratio tissues (13.94±5.94 per 100 cells vs 8.04±3.99 per 100 cells,

conclusionCho/Cr ratios correlate with the distribution of CSLCs in high-grade gliomas, and this may assist in identifying foci enriched with CSLCs and thus improve the management of high-grade gliomas.

Indexed as

1H-MRScancer stem-like cellsCho/Crcholinecreatinehigh-grade glioma

Identifiers

PMID28115854
PMCPMC5221654
OpenAlexW2568115178

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.