Evidence map›Paper›PMID 28115596›Full record

ArticleRNA (New York, N.Y.)2017

Osmium tetroxide as a probe of RNA structure.

Jing Zhang, Danbin Li, Jun Zhang, Dongrong Chen, Alastair I H Murchie

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jing ZhangFudan University Pudong Medical Center, Pudong, Shanghai 201399, China.
Danbin LiInstitute of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai 200032, China.
Jun ZhangInstitute of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai 200032, China.
Dongrong ChenFudan University Pudong Medical Center, Pudong, Shanghai 201399, China.
Alastair I H MurchieFudan University Pudong Medical Center, Pudong, Shanghai 201399, China.
Shanghai Medical College of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Structured RNAs have a central role in cellular function. The capability of structured RNAs to adopt fixed architectural structures or undergo dynamic conformational changes contributes to their diverse role in the regulation of gene expression. Although numerous biophysical and biochemical tools have been developed to study structured RNAs, there is a continuing need for the development of new methods for the investigation of RNA structures, especially methods that allow RNA structure to be studied in solution close to its native cellular conditions. Here we use osmium tetroxide (OsO

Indexed as

Base SequenceMolecular ProbesNucleic Acid ConformationOsmium TetroxideRiboswitchRNA, Transfer, AspStaining and LabelingUracilMolecular ProbesOsmium TetroxideRiboswitchRNA, Transfer, AspUracilchemical probeosmium tetroxideRNARNA structure

Identifiers

PMID28115596
PMCPMC5340912
OpenAlexW2581888268

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.