Evidence map›Paper›PMID 28115593›Full record

ArticleBioscience reports2017

Serum microRNAs are non-invasive biomarkers for the presence and progression of subarachnoid haemorrhage.

Nian-Sheng Lai, Jia-Qi Zhang, Fei-Yun Qin, Bin Sheng, Xing-Gen Fang, Zhen-Bao Li

Abstract read
In one paragraph

Article in Bioscience reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nian-Sheng LaiDepartment of Neurosurgery, The First Affiliated Hospital of Wannan Medical College, Wuhu City, Anhui 241001, China.
Jia-Qi ZhangDepartment of Neurosurgery, Xinxiang Central Hospital , Xinxiang City, Henan 453000, China.
Fei-Yun QinDepartment of Neurosurgery, The First Affiliated Hospital of Wannan Medical College, Wuhu City, Anhui 241001, China.
Bin ShengDepartment of Neurosurgery, The First Affiliated Hospital of Wannan Medical College, Wuhu City, Anhui 241001, China.
Xing-Gen FangDepartment of Neurosurgery, The First Affiliated Hospital of Wannan Medical College, Wuhu City, Anhui 241001, China.
Zhen-Bao LiDepartment of Neurosurgery, The First Affiliated Hospital of Wannan Medical College, Wuhu City, Anhui 241001, China zhenbaoli123@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

miRNAs are important regulators of translation and have been associated with the pathogenesis of a number of cardiovascular diseases including stroke and may be possible prognostic biomarkers. The purpose of the present study was to determine the expression levels of miRNAs in the sera of subarachnoid haemorrhage (SAH) patients and to evaluate their relationships with the severity and clinical outcome of SAH. Serum samples on day 3 after the onset of SAH were subjected to microarray analysis with Exqion miRCURY

Indexed as

AdultBiomarkersDisease ProgressionGene Expression ProfilingGene Expression RegulationHumansMicroRNAsROC CurveSubarachnoid HemorrhageBiomarkersMicroRNAsMIRN1297 microRNA, humanMIRN502 microRNA, humanBiomarkersMicroRNAsqRT-PCRSubarachnoid hemorrhage

Identifiers

PMID28115593
PMCPMC5322746

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.