Evidence map›Paper›PMID 28115352›Full record

ArticleAntimicrobial agents and chemotherapy2017

Clinical and Microbiological Characteristics of Breakthrough Candidemia in Allogeneic Hematopoietic Stem Cell Transplant Recipients in a Japanese Hospital.

Muneyoshi Kimura, Hideki Araoka, Hisashi Yamamoto, Yuki Asano-Mori, Shigeki Nakamura, Satoshi Yamagoe, Hideaki Ohno, Yoshitsugu Miyazaki, Masahiro Abe, Mitsuhiro Yuasa and 11 more

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04619147 (Invasive Fungal Infections in Patients Following Stem Cell Transplant), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04619147 completednot on this mapstarted 2022, after this paper: background citation

Invasive Fungal Infections in Patients Following Stem Cell Transplant

TypeobservationalSponsorPeter MacCallum Cancer Centre, AustraliaRan2022 to 2024Enrolled300ConditionsInvasive Fungal Infections, Stem Cell Transplant ComplicationsArmsNo intervention
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Non-Journal of fungi (Basel, Switzerland) · 2022
    Review
  6. Review
  7. Factors Associated with Breakthrough Fungemia Caused byAntimicrobial agents and chemotherapy · 2022
    Article
  8. Article
  9. Article
  10. Febrile Neutropenia in Acute Leukemia. Epidemiology, Etiology, Pathophysiology and Treatment.Mediterranean journal of hematology and infectious diseases · 2020
    Review
  11. Review
  12. Candidemia due toCurrent medical mycology · 2019
    Article
  13. Antimicrobial agents and chemotherapy · 2019
    Article
  14. Article
  15. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 4 institutions in 1 country.

Muneyoshi KimuraDepartment of Infectious Diseases, Toranomon Hospital, Tokyo, Japan.
Hideki AraokaDepartment of Infectious Diseases, Toranomon Hospital, Tokyo, Japan h-araoka@toranomon.gr.jp.
Hisashi YamamotoDepartment of Hematology, Toranomon Hospital, Tokyo, Japan.
Yuki Asano-MoriDepartment of Hematology, Toranomon Hospital, Tokyo, Japan.
Shigeki NakamuraDepartment of Chemotherapy and Mycoses, National Institute of Infectious Diseases, Tokyo, Japan.
Satoshi YamagoeDepartment of Chemotherapy and Mycoses, National Institute of Infectious Diseases, Tokyo, Japan.
Hideaki OhnoDepartment of Infectious Diseases and Infection Control, Saitama Medical Center, Saitama Medical University, Saitama, Japan.
Yoshitsugu MiyazakiDepartment of Chemotherapy and Mycoses, National Institute of Infectious Diseases, Tokyo, Japan.
Masahiro AbeDepartment of Infectious Diseases, Toranomon Hospital, Tokyo, Japan.
Mitsuhiro YuasaDepartment of Hematology, Toranomon Hospital, Tokyo, Japan.
Daisuke KajiDepartment of Hematology, Toranomon Hospital, Tokyo, Japan.
Kosei KageyamaDepartment of Hematology, Toranomon Hospital, Tokyo, Japan.
Aya NishidaDepartment of Hematology, Toranomon Hospital, Tokyo, Japan.
Kazuya IshiwataDepartment of Hematology, Toranomon Hospital, Tokyo, Japan.
Shinsuke TakagiDepartment of Hematology, Toranomon Hospital, Tokyo, Japan.
Go YamamotoDepartment of Hematology, Toranomon Hospital, Tokyo, Japan.
Naoyuki UchidaDepartment of Hematology, Toranomon Hospital, Tokyo, Japan.
Koji IzutsuDepartment of Hematology, Toranomon Hospital, Tokyo, Japan.
Atsushi WakeDepartment of Hematology, Toranomon Hospital, Tokyo, Japan.
Shuichi TaniguchiDepartment of Hematology, Toranomon Hospital, Tokyo, Japan.
Akiko YoneyamaDepartment of Infectious Diseases, Toranomon Hospital, Tokyo, Japan.
Toranomon Hospital · JPNational Institute of Infectious Diseases · JPOkinaka Memorial Institute for Medical ResearchSocial Insurance Saitama Chuo Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Few data on breakthrough candidemia (BC), defined as candidemia that develops on administration of antifungal agents (AFAs), in allogeneic hematopoietic stem cell transplant (allo-HSCT) recipients are available. The medical and microbiological records of recipients of an allo-HSCT obtained between December 2008 and December 2014 were reviewed. Of 768 allo-HSCT cases, 26 developed BC. Among the 26 causative strains, 22 strains were stored and identified by sequencing. The following species were isolated:

Indexed as

AdolescentAdultAgedAmphotericin BAntifungal AgentsAntineoplastic AgentsCandidaCandidemiaEchinocandinsFemaleHematologic NeoplasmsHematopoietic Stem Cell TransplantationHospitalsHumansItraconazoleJapanAmphotericin BAntifungal AgentsAntineoplastic AgentsEchinocandinsItraconazoleLipopeptidesliposomal amphotericin BMicafunginSteroidsVoriconazoleallogeneic hematopoietic stem cell transplantationbreakthrough candidemiacandidemiamicafunginsteroids

Identifiers

PMID28115352
PMCPMC5365651
OpenAlexW2582209117

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.