Evidence map›Paper›PMID 28115345›Full record

ArticleAntimicrobial agents and chemotherapy2017

Subinhibitory Concentrations of Bacteriostatic Antibiotics Induce

Pavel Kudrin, Vallo Varik, Sofia Raquel Alves Oliveira, Jelena Beljantseva, Teresa Del Peso Santos, Ievgen Dzhygyr, Dominik Rejman, Felipe Cava, Tanel Tenson, Vasili Hauryliuk

Open access · hybridAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 70 citations in OpenAlex.

  1. Trial
  2. In the shadow of antibiotics.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Adaptation of a fluoroquinolone-sensitiveRoyal Society open science · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Survival ofFrontiers in microbiology · 2023
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. The extended (p)ppGpp family: New dimensions in Stress response.Current research in microbial sciences · 2021
    Review
  13. Review
  14. Isolation of Persister Cells ofInternational journal of molecular sciences · 2021
    Article
  15. Article
  16. Article
  17. Microbiology and molecular biology reviews : MMBR · 2020
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Pavel KudrinUniversity of Tartu, Institute of Technology, Tartu, Estonia.
Vallo VarikUniversity of Tartu, Institute of Technology, Tartu, Estonia.
Sofia Raquel Alves OliveiraUniversity of Tartu, Institute of Technology, Tartu, Estonia.
Jelena BeljantsevaUniversity of Tartu, Institute of Technology, Tartu, Estonia.
Teresa Del Peso SantosDepartment of Molecular Biology, Umeå University, Umeå, Sweden.
Ievgen DzhygyrDepartment of Molecular Biology, Umeå University, Umeå, Sweden.
Dominik RejmanInstitute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, v.v.i., Prague, Czech Republic.
Felipe CavaDepartment of Molecular Biology, Umeå University, Umeå, Sweden.
Tanel TensonUniversity of Tartu, Institute of Technology, Tartu, Estonia.
Vasili HauryliukUniversity of Tartu, Institute of Technology, Tartu, Estonia vasili.hauryliuk@umu.se.ORCID 0000-0003-2389-5057
University of Tartu · EEUmeå University · SECzech Academy of Sciences, Institute of Organic Chemistry and Biochemistry · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The nucleotide (p)ppGpp is a key regulator of bacterial metabolism, growth, stress tolerance, and virulence. During amino acid starvation, the

Indexed as

Drug ToleranceAnti-Bacterial Agentsbeta-LactamsChloramphenicolDrug InteractionsEscherichia coliGuanosine TetraphosphateIsoleucine-tRNA LigaseLigasesMupirocinProtein BiosynthesisRibosomesRNA, TransferSubcellular FractionsTetracyclineTetrahydrofolate Dehydrogenaseadenosine 5',5'''-triphosphoguanosine-3'''-diphosphateAnti-Bacterial Agentsbeta-LactamsChloramphenicolguanosine 3',5'-polyphosphate synthetasesGuanosine TetraphosphateIsoleucine-tRNA LigaseLigasesMupirocinRNA, TransferTetracyclineTetrahydrofolate DehydrogenaseThiostreptonTrimethoprimantibioticsmupirocinpersistenceppGppRelAribosomesthiostreptontolerancetrimethoprimβ-lactam

Identifiers

PMID28115345
PMCPMC5365698
OpenAlexW2582932073

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.