ArticleJournal of orthopaedic surgery and research2017
Correlation between change in muscle excursion and collagen content after tendon rupture and delayed repair.
Article in Journal of orthopaedic surgery and research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- Effects of Single, Maximal Intensity Exercise Unit on Selected Markers of Bone and Connective Tissue Turnover in Young Men.Journal of clinical medicine · 2026Article
- FGF gene expression in injured tendons as a prognostic biomarker of 1-year patient outcome after Achilles tendon repair.Journal of experimental orthopaedics · 2021Article
- Signature molecular changes in the skeletal muscle of hindlimb unloaded mice.Biochemistry and biophysics reports · 2021Article
- Proteomics identifies differences in fibrotic potential of extracellular vesicles from human tendon and muscle fibroblasts.Cell communication and signaling : CCS · 2020Article
- Exploring the Pathological Role of Collagen in Paravertebral Muscle in the Progression of Idiopathic Scoliosis.BioMed research international · 2020Article
- Tendon split lengthening technique for flexor hallucis longus tendon rupture.Journal of orthopaedic surgery and research · 2017Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe objectives of the present study were to compare changes in muscle excursion, total collagen, and collagen subtypes after tenotomy over time and after delayed tendon repair.
methodsTenotomy on the extensor digitorum tendon of the right second toes of 48 New Zealand White rabbits was performed; toes on the left leg were used as controls. Passive muscle excursion, total collagen content, and type I, III, and IV collagen contents were measured at 1, 2, 4, and 6 weeks after tenotomy. Next, passive muscle excursion and total collagen content were measured at 8 weeks after delayed tendon repair at 1, 2, 4, and 6 weeks after a tenotomy.
resultsPassive muscle excursion decreased sequentially over time after tenotomy. Meanwhile, total collagen increased over time. These changes were significant after 4 weeks of injury. Type I collagen significantly increased, type III collagen significantly decreased, and type IV collagen had no significant change over time. Passive muscle excursion was negatively correlated with total collagen and type I collagen after tenotomy at each time point after tenotomy (p < 0.05). After tendon repair, increases in total collagen content after tenotomy were not reversed, despite early repairs at 1 and 2 weeks after tenotomy.
conclusionsIncreases in type I collagen were found to be associated with decreased excursion after tendon rupture. The increase in collagen that was observed after tenotomy was not reversed by repair within 8 weeks.
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Registered trials
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