ArticleBMC musculoskeletal disorders2017
Induced membrane technique for the treatment of chronic hematogenous tibia osteomyelitis.
Article in BMC musculoskeletal disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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13 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Antibiotic-laden bone cement for diabetic foot infected wounds: A systematic review and meta-analysis.Frontiers in endocrinology · 2023Pooled it
- ["Chongqing experiences" in treatment of bone infections].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026Review
- Clinical outcome of chronic haematogenous osteomyelitis of the femur or tibia in adults using selective segmental osteotomy and induced membrane technique.BMC surgery · 2025Article
- Prospects and challenges for the application of tissue engineering technologies in the treatment of bone infections.Bone research · 2024Review
- Impact of VSD therapy on surgical outcomes, inflammatory markers, and functional rehabilitation in patients with secondary bone infection following tibial fracture surgery.Frontiers in cellular and infection microbiology · 2024Article
- [Clinical efficacy of antibiotic bone cement combined with vacuum sealing drainage in treating diabetes mellitus complicated with necrotizing fasciitis].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2023Observational
- Enhancing Bone Grafting Outcomes: A Comprehensive Review of Antibacterial Artificial Composite Bone Scaffolds.Medical science monitor : international medical journal of experimental and clinical research · 2023Review
- Clinical effects of early debridement, internal fixation, and Masquelet technique for childhood chronic haematogenous osteomyelitis of long bones.Journal of orthopaedic surgery and research · 2023Article
- Application of the induced membrane technique of tibia using extracorporeal vs. intracorporeal formation of a cement spacer: a retrospective study.BMC musculoskeletal disorders · 2022Article
- Management of chronic osteomyelitis of the femur and tibia: a scoping review.EFORT open reviews · 2021Article
- Antibiotic cement plate composite structure internal fixation after debridement of bone infection.Scientific reports · 2021Article
- MRI Manifestations and Diagnostic Value of Chronic Osteomyelitis.Journal of healthcare engineering · 2021Article
- Postoperative Chronic Osteomyelitis in the Long Bones - Current Knowledge and Management of the Problem.Revista brasileira de ortopedia · 2019Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic hematogenous osteomyelitis often results from the improper treatment of acute hematogenous osteomyelitis. At present, there is lack of uniform standards for the treatment, and the clinical features of the disease are unclear. The purpose of this study was to explore the clinical efficacy and complications of chronic hematogenous tibia osteomyelitis treated with the induced membrane technique.
methodsA retrospective analysis of the chronic hematogenous tibia osteomyelitis patients in our department admitted from January 2013 to February 2014 and treated with the induced membrane two-stage surgical technique was performed. The defects were filled with antibiotic-loaded polymethyl methacrylate (PMMA) cement after radical debridement, and bone grafts were implanted to repair the defects after 6 to 8 weeks.
resultsA total of 15 cases were admitted in this study, including 13 men and 2 women with a mean age of 34 years (6 to 51). The mean duration of bone infection was 142 months (3 to 361). All patients were cured with an average follow-up of 25 months (24 to 28). Radiographic bone union occurred in 5.3 months (3 to 8), and full weight bearing occurred in 6.7 months (4 to 10). No recurrence of infection was noted at the last follow-up. Two cases required repeated debridement before grafting due to recurrent infection. One patient had a small bone diameter due to insufficient grafting, and one patient had limitation of knee activity.
conclusionsThe induced membrane technique for the treatment of chronic hematogenous tibia osteomyelitis is an effective and reliable method. Thorough debridement and wound closure at the first stage is essential for infection control as well as sufficient grafting at the second stage to ensure bone union.
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