Evidence map›Paper›PMID 28114900›Full record

ArticleBMC nephrology2017

The reverse remodeling of the aorta in patients after renal transplantation - the value of aortic stiffness index: prospective echocardiographic study.

Tomasz Zapolski, Jacek Furmaga, Andrzej Jaroszyński, Anna Wysocka, Sławomir Rudzki, Andrzej P Wysokiński

Open access · goldAbstract read
In one paragraph

Article in BMC nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Observational
  2. Article
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  4. Local elasticity of the aorta in patients with type 2 diabetes mellitus.The Journal of international medical research · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Tomasz ZapolskiDepartment of Cardiology, Medical University of Lublin, ul. Jaczewskiego 8, 20-950, Lublin, Poland. zapolia@wp.pl.
Jacek FurmagaDepartment of General and Transplant Surgery and Nutritional Treatment, Medical University of Lublin, Lublin, Poland.
Andrzej JaroszyńskiDepartment of Family Medicine, Medical University of Lublin, Lublin, Poland.
Anna WysockaDepartment of Cardiology, Medical University of Lublin, ul. Jaczewskiego 8, 20-950, Lublin, Poland.
Sławomir RudzkiDepartment of General and Transplant Surgery and Nutritional Treatment, Medical University of Lublin, Lublin, Poland.
Andrzej P WysokińskiDepartment of Cardiology, Medical University of Lublin, ul. Jaczewskiego 8, 20-950, Lublin, Poland.
Medical University of Lublin · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAtherosclerosis is regarded as a combination of two major separate diseases: atherosis and sclerosis. Sclerotic component depends on deterioration of elastic properties of the aortic wall and is called aortic stiffness. The most valuable, non-invasive method of aortic stiffness assessment is echocardiography, which allows to calculate the aortic stiffness index (ASI). ASI is an independent predictor of all-cause and cardiovascular mortality in different groups of patients. The main aim of study was the assessment of the aortic reverse remodeling in patients with end-stage renal disease (ESRD) after renal transplantation (RT).

methodsStudy group involved 42 patients aged 43.3 ± 12.6 years, including 19 women aged 49.9 ± 10.9 years and 23 men aged 41.5 ± 12.91 years, who have undergone RT from non-related renal transplant donors, The study protocol has been consisted of 5 stages: 1 week after RT, 3 months after RT, 6 months after RT, 1 year after RT and 3 years after RT. The echocardiographic examination was performed and measurements of Ao

resultsThe improvement of indices characterizing the elastic properties of aorta were noted. These changes attained the statistically significant level only at the end of the observation. ASI just after RT was equal - 4.65 ± 1.58, three months after RT - 4.54 ± 1.49, six months after RT - 4.59 ± 1.61, one year after RT - 4.35 ± 1.21 and three years after RT - 3.35 ± 1.29, while AD reached respectively - 6.55 ± 3.76 cm

conclusionsThere is a relationship between renal transplantation and improvement of the aortic elastic properties. The recovery of the renal function allows to initiate the reparative processes leading to at least partial restitution of the structure and features of the aorta, which is called reverse remodelling. Improvement of aortic wall elastic properties after renal transplantation is a continuous and prolonged process.

Indexed as

Kidney TransplantationVascular RemodelingVascular StiffnessAdultAortaEchocardiographyFemaleHumansKidney Failure, ChronicMaleMiddle AgedProspective StudiesTreatment OutcomeAortic stiffness indexEnd-stage renal diseaseRenal transplantationStiffness of aorta

Identifiers

PMID28114900
PMCPMC5260005
OpenAlexW2582159763

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.