Evidence map›Paper›PMID 28114869›Full record

ArticleStress (Amsterdam, Netherlands)2017

Salivary cortisol and cognitive development in infants from low-income communities.

Eric D Finegood, Claire Wyman, Thomas G O'Connor, Clancy B Blair, Family Life Project Investigators

Abstract read
In one paragraph

Article in Stress (Amsterdam, Netherlands), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
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  3. Observational
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eric D Finegooda Department of Applied Psychology , New York University , NY , USA.
Claire Wymanb Department of Psychiatry , University of Rochester Medical Center , NY , USA.
Thomas G O'Connorb Department of Psychiatry , University of Rochester Medical Center , NY , USA.
Clancy B Blaira Department of Applied Psychology , New York University , NY , USA.
Family Life Project Investigatorsc Center for Developmental Science, University of North Carolina at Chapel Hill , NC , USA.

Funding

Temperment, Psychobiological, and Cognitive PredictorsP01HD039667 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BURCHINAL, MARGARET RUTH · 2002 to 2011
$29.1M
NICHD NIH HHS P01 HD039667
6 · The paper itself

Abstract

Early stress exposure is proposed to have significant lasting effects on cognitive development. The glucocorticoid hormone cortisol, a product of the hypothalamic-pituitary-adrenal (HPA) axis, is a particular focus of research, however, the majority of past research has been based on studies of older children and adults. Evidence linking cortisol levels in infancy with cognitive development is lacking. In a large cohort sample of infants (N = 1091) oversampled for psychosocial risk, we tested whether basal cortisol levels and cortisol reactivity to emotional stressors administered at 7 and 15 months of age were associated with cognitive development measured at 15 months. Cognitive development was measured using the Mental Development Index of the Bayley Scales of Infant Development. Multiple regression analyses indicated that basal cortisol levels at 15 months, and to a lesser extent at seven months, were inversely associated with infant cognitive development after adjusting for psychosocial and obstetric risk. The findings provide some of the first evidence that HPA axis activity in infancy is associated with early cognitive development.

Indexed as

Child DevelopmentCognitionFemaleHumansHydrocortisoneHypothalamo-Hypophyseal SystemInfantLearningMalePituitary-Adrenal SystemPovertySalivaStress, PsychologicalHydrocortisoneallostatic loadcognitive developmentCortisolHPA axisinfancystress

Identifiers

PMID28114869
PMCPMC5615401

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.