Evidence map›Paper›PMID 28114449›Full record

ArticleJournal of biomedical optics2017

Wearable near-infrared optical probe for continuous monitoring during breast cancer neoadjuvant chemotherapy infusions.

Fei Teng, Timothy Cormier, Alexis Sauer-Budge, Rachita Chaudhury, Vivian Pera, Raeef Istfan, David Chargin, Samuel Brookfield, Naomi Yu Ko, Darren M Roblyer

Registry-linked trialAbstract read
In one paragraph

Article in Journal of biomedical optics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06360809 (Prehabilitation Exercise Program in Breast Cancer), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06360809 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Prehabilitation Exercise Program in Breast Cancer: Effects on Quality of Life and Tumor Microenvironment (PEP_BC)

TypeinterventionalSponsorInstitut Nacional d'Educacio Fisica de CatalunyaRan2024 to 2025Enrolled76ConditionsBreast CancerArmsPrehabilitation exercise program
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fei TengBoston University, Department of Electrical and Computer Engineering and Photonics Center, 8 Saint Mary's Street, Boston, Massachusetts 02215, United States.
Timothy CormierBoston University, Fraunhofer Center for Manufacturing Innovation, 15 Saint Mary's Street, Brookline, Massachusetts 02446, United States.
Alexis Sauer-BudgeBoston University, Fraunhofer Center for Manufacturing Innovation, 15 Saint Mary's Street, Brookline, Massachusetts 02446, United States.
Rachita ChaudhuryBoston University, Department of Biomedical Engineering, 44 Cummington Mall, Boston, Massachusetts 02215, United States.
Vivian PeraBoston University, Department of Biomedical Engineering, 44 Cummington Mall, Boston, Massachusetts 02215, United States.
Raeef IstfanBoston University, Department of Biomedical Engineering, 44 Cummington Mall, Boston, Massachusetts 02215, United States.
David CharginBoston University, Fraunhofer Center for Manufacturing Innovation, 15 Saint Mary's Street, Brookline, Massachusetts 02446, United States.
Samuel BrookfieldBoston University, Fraunhofer Center for Manufacturing Innovation, 15 Saint Mary's Street, Brookline, Massachusetts 02446, United States.
Naomi Yu KoBoston Medical Center, Section of Hematology and Oncology, Women's Health Unit, 801 Massachusetts Avenue, First Floor, Boston, Massachusetts 02118, United States.
Darren M RoblyerBoston University, Department of Biomedical Engineering, 44 Cummington Mall, Boston, Massachusetts 02215, United States.

Funding

Center for Innovation in Point of Care Technologies for the Future of Cancer CareU54EB015403 · NIBIB · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI KLAPPERICH, CATHERINE M. · 2012 to 2016
$8.9M
NIBIB NIH HHS U54 EB015403
6 · The paper itself

Abstract

We present a new continuous-wave wearable diffuse optical probe aimed at investigating the hemodynamic response of locally advanced breast cancer patients during neoadjuvant chemotherapy infusions. The system consists of a flexible printed circuit board that supports an array of six dual wavelength surface-mount LED and photodiode pairs. The probe is encased in a soft silicone housing that conforms to natural breast shape. Probe performance was evaluated using tissue-simulating phantoms and in vivo normal volunteer measurements. High SNR (71 dB), low source-detector crosstalk ( ? 60 ?? dB ), high measurement precision (0.17%), and good thermal stability (0.22% V rms / ° C ) were achieved in phantom studies. A cuff occlusion experiment was performed on the forearm of a healthy volunteer to demonstrate the ability to track rapid hemodynamic changes. Proof-of-principle normal volunteer measurements were taken to demonstrate the ability to collect continuous in vivo breast measurements. This wearable probe is a first of its kind tool to explore prognostic hemodynamic changes during chemotherapy in breast cancer patients.

Indexed as

Wearable Electronic DevicesBreastBreast NeoplasmsFemaleHemodynamicsHumansNeoadjuvant TherapyPhantoms, Imaging

Identifiers

PMID28114449
PMCPMC5289133

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.