Evidence map›Paper›PMID 28114448›Full record

ArticleJournal of biomedical optics2017

Design of a portable imager for near-infrared visualization of cutaneous wounds.

Zhaoqiang Peng, Jun Zhou, Ashley Dacy, Deyin Zhao, Vasant Kearney, Weidong Zhou, Liping Tang, Wenjing Hu

Open access · goldAbstract read
In one paragraph

Article in Journal of biomedical optics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Imaging in Chronic Wound Diagnostics.Advances in wound care · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Zhaoqiang PengUniversity of Texas at Arlington, Department of Electrical Engineering, P.O. Box 19016, Arlington, Texas 76019, United States.
Jun ZhouUniversity of Texas at Arlington, Department of Bioengineering, P.O. Box 19138, Arlington, Texas 76019, United States.
Ashley DacyUniversity of Texas at Arlington, Department of Bioengineering, P.O. Box 19138, Arlington, Texas 76019, United States.
Deyin ZhaoUniversity of Texas at Arlington, Department of Electrical Engineering, P.O. Box 19016, Arlington, Texas 76019, United States.
Vasant KearneyUniversity of Texas at Arlington, Department of Bioengineering, P.O. Box 19138, Arlington, Texas 76019, United States.
Weidong ZhouUniversity of Texas at Arlington, Department of Electrical Engineering, P.O. Box 19016, Arlington, Texas 76019, United States.
Liping TangUniversity of Texas at Arlington, Department of Bioengineering, P.O. Box 19138, Arlington, Texas 76019, United States.
Wenjing HuProgenitec Inc., 917 Parktree Drive, Arlington, Texas 76015, United States.
The University of Texas at Arlington · USProgenitec (United States) · US

Funding

A novel optical imaging probe system for assessing wound healing and infectionR44AR064650 · NIAMS · PROGENITEC, INC. · PI HU, WENJING · 2017 to 2018
$1.3M
DEVELOPMENT OF RATIOMETRIC IMAGING PROBE SYSTEM FOR MONITORING INFLAMMATIONR44GM101776 · NIGMS · PROGENITEC, INC. · PI HU, WENJING · 2016 to 2017
$1.3M
DEVELOPMENT OF RATIOMETRIC IMAGING PROBE SYSTEM FOR MONITORING INFLAMMATIONR43GM101776 · NIGMS · PROGENITEC, INC. · PI HU, WENJING · 2012 to 2012
$220k
A novel optical imaging probe system for assessing wound healing and infectionR43AR064650 · NIAMS · PROGENITEC, INC. · PI HU, WENJING · 2013 to 2013
$200k
NIAMS NIH HHS R43 AR064650NIAMS NIH HHS R44 AR064650NIGMS NIH HHS R43 GM101776NIGMS NIH HHS R44 GM101776
6 · The paper itself

Abstract

A portable imager developed for real-time imaging of cutaneous wounds in research settings is described. The imager consists of a high-resolution near-infrared CCD camera capable of detecting both bioluminescence and fluorescence illuminated by an LED ring with a rotatable filter wheel. All external components are integrated into a compact camera attachment. The device is demonstrated to have competitive performance with a commercial animal imaging enclosure box setup in beam uniformity and sensitivity. Specifically, the device was used to visualize the bioluminescence associated with increased reactive oxygen species activity during the wound healing process in a cutaneous wound inflammation model. In addition, this device was employed to observe the fluorescence associated with the activity of matrix metalloproteinases in a mouse lipopolysaccharide-induced infection model. Our results support the use of the portable imager design as a noninvasive and real-time imaging tool to assess the extent of wound inflammation and infection.

Indexed as

Wound HealingAnimalsFluorescenceOptical ImagingReactive Oxygen SpeciesSkinSpectroscopy, Near-InfraredWounds and InjuriesReactive Oxygen Species

Identifiers

PMID28114448
PMCPMC5234331
OpenAlexW2576891440

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.