Evidence map›Paper›PMID 28114347›Full record

ArticlePloS one2017

Genetic HLA Study of Kurds in Iraq, Iran and Tbilisi (Caucasus, Georgia): Relatedness and Medical Implications.

Antonio Arnaiz-Villena, Jose Palacio-Grüber, Ester Muñiz, Cristina Campos, Javier Alonso-Rubio, Eduardo Gomez-Casado, Shadallah Fareq Salih, Manuel Martin-Villa, Rawand Al-Qadi

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In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Antonio Arnaiz-VillenaDepartment of Immunology, University Complutense, School of Medicine, Madrid Regional Blood Center, Madrid, Spain.
Jose Palacio-GrüberDepartment of Immunology, University Complutense, School of Medicine, Madrid Regional Blood Center, Madrid, Spain.
Ester MuñizDepartment of Immunology, University Complutense, School of Medicine, Madrid Regional Blood Center, Madrid, Spain.
Cristina CamposDepartment of Immunology, University Complutense, School of Medicine, Madrid Regional Blood Center, Madrid, Spain.
Javier Alonso-RubioDepartment of Immunology, University Complutense, School of Medicine, Madrid Regional Blood Center, Madrid, Spain.
Eduardo Gomez-CasadoDepartment of Inmunología Animal, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Autopista A6, Hipódromo, Madrid, Spain.
Shadallah Fareq SalihHLA Typing Department, Dohuk Specialized Laboratory Center, Dohuk, Iraq.
Manuel Martin-VillaDepartment of Immunology, University Complutense, School of Medicine, Madrid Regional Blood Center, Madrid, Spain.
Rawand Al-QadiHLA Typing Department, Dohuk Specialized Laboratory Center, Dohuk, Iraq.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kurds from Iraq (Dohuk and Erbil Area, North Iraq) have been analyzed for HLA genes. Their HLA genetic profile has been compared with that of other Kurd groups from Iran and Tbilisi (Georgia, Caucasus) and also Worldwide populations. A total of 7,746 HLA chromosomes have been used. Genetic distances, NJ dendrograms and correspondence analyses have been carried out. Haplotype HLA-B*52-DRB1*15 is present in all three analyzed Kurd populations. HLA-A*02-B*51-DRB1*11 is present in Iraq and Georgia Kurds. Haplotypes common to Iran and Iraq Kurds are HLA DRB1*11-DQB1*03, HLA DRB1*03-DQB1*02 and others in a lower frequency. Our HLA study conclusions are that Kurds most probably belong to an ancient Mediterranean / Middle East / Caucasian genetic substratum and that present results and those previously obtained by us in Kurds may be useful for Medicine in future Kurd transplantation programs, HLA Epidemiology (HLA linked diseases) and Pharmacogenomics (HLA-associated drug side effects) and also for Anthropology. It is discussed that one of the most ancient Kurd ancestor groups is in Hurrians (2,000 years BC).

Indexed as

Georgia (Republic)HaplotypesHLA AntigensIranIraqPhylogenyHLA Antigens

Identifiers

PMID28114347
PMCPMC5256937

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