Evidence map›Paper›PMID 28112557›Full record

ArticleAJR. American journal of roentgenology2017

Radiology Reports With Hyperlinks Improve Target Lesion Selection and Measurement Concordance in Cancer Trials.

Laura B Machado, Andrea B Apolo, Seth M Steinberg, Les R Folio

Abstract read
In one paragraph

Article in AJR. American journal of roentgenology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Multimedia-enhanced Radiology Reports: Concept, Components, and Challenges.Radiographics : a review publication of the Radiological Society of North America, Inc
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Laura B Machado1 Radiology and Imaging Sciences, National Institutes of Health Clinical Center, 9000 Rockville Pike, Bldg 10, Bethesda, MD 20892.
Andrea B Apolo2 Genitourinary Malignancies Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD.
Seth M Steinberg3 Biostatistics and Data Management Section, Office of the Clinical Director, National Cancer Institute, Rockville, MD.
Les R Folio1 Radiology and Imaging Sciences, National Institutes of Health Clinical Center, 9000 Rockville Pike, Bldg 10, Bethesda, MD 20892.

Funding

Bladder Cancer ProgramZIABC011351 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI APOLO, ANDREA · 2010 to 2025
$9.4M
Intramural NIH HHS ZIA BC011351
6 · The paper itself

Abstract

objectiveRadiology reports often lack the measurements of target lesions that are needed for oncology clinical trials. When available, the measurements in the radiology reports often do not match those in the records used to calculate therapeutic response. This study assessed the clinical value of hyperlinked tumor measurements in multimedia-enhanced radiology reports in the PACS and the inclusion of a radiologist assistant in the process of assessing tumor burden. MATERIALS AND

methodsWe assessed 489 target lesions in 232 CT examinations of 71 patients with metastatic genitourinary cancer enrolled in two therapeutic trials. We analyzed target lesion selection and measurement concordance between oncology records (used to calculate therapeutic response) and two types of radiology reports in the PACS: multimedia-enhanced radiology reports and text-only reports. For statistical tests, we used the Wilcoxon signed rank, Wilcoxon rank sum test, and Fisher method to combine p values from the paired and unpaired results. The Fisher exact test was used to compare overall measurement concordance.

resultsConcordance on target lesion selection was greater for multimedia-enhanced radiology reports (78%) than the text-only reports (52%) (p = 0.0050). There was also improved overall measurement concordance with the multimedia-enhanced radiology reports (68%) compared with the text-only reports (38%) (p < 0.0001).

conclusionCompared with text-only reports, hyperlinked multimedia-enhanced radiology reports improved concordance of target lesion selection and measurement with the measurements used to calculate therapeutic response.

Indexed as

Response Evaluation Criteria in Solid TumorsClinical Trials as TopicData MiningDocumentationHumansMedical Record LinkageNatural Language ProcessingRadiology Information SystemsReproducibility of ResultsSensitivity and SpecificityTomography, X-Ray ComputedUrogenital Neoplasmshyperlinksmultimediaradiology reportsResponse Evaluation Criteria in Solid Tumors (RECIST) 1.1tumor assessment

Identifiers

PMID28112557
PMCPMC6762032

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.