Evidence map›Paper›PMID 28112275›Full record

ArticleScientific reports2017

Cell Death Mechanisms in Tumoral and Non-Tumoral Human Cell Lines Triggered by Photodynamic Treatments: Apoptosis, Necrosis and Parthanatos.

J Soriano, I Mora-Espí, M E Alea-Reyes, L Pérez-García, L Barrios, E Ibáñez, C Nogués

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 76 citations in OpenAlex.

  1. Shedding light on the cancer cell death mechanism in photodynamic therapy.Apoptosis : an international journal on programmed cell death · 2026
    Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Evaluation of CoFeInternational journal of molecular sciences · 2025
    Article
  8. Review
  9. Enhancing antitumour immunity with photodynamic therapy.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
  10. BODIPY-fused uracil: synthesis, photophysical properties, and applications.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2024
    Article
  11. Review
  12. Article
  13. Metabolomics analysis of MnORSC advances · 2023
    Article
  14. Supercritical COChemistry of materials : a publication of the American Chemical Society · 2023
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Photodynamic Therapy Induced Cell Death Mechanisms in Breast Cancer.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

J SorianoDepartament de Biologia Cel·lular, Fisiologia i Immunologia, Universitat Autònoma de Barcelona, Spain.
I Mora-EspíDepartament de Biologia Cel·lular, Fisiologia i Immunologia, Universitat Autònoma de Barcelona, Spain.
M E Alea-ReyesDepartament de Farmacologia, toxicologia i Química Terapèutica and Institut de Nanociència i Nanotecnologia (IN2UB), Universitat de Barcelona, Spain.
L Pérez-GarcíaDepartament de Farmacologia, toxicologia i Química Terapèutica and Institut de Nanociència i Nanotecnologia (IN2UB), Universitat de Barcelona, Spain.
L BarriosDepartament de Biologia Cel·lular, Fisiologia i Immunologia, Universitat Autònoma de Barcelona, Spain.
E IbáñezDepartament de Biologia Cel·lular, Fisiologia i Immunologia, Universitat Autònoma de Barcelona, Spain.
C NoguésDepartament de Biologia Cel·lular, Fisiologia i Immunologia, Universitat Autònoma de Barcelona, Spain.
Universitat Autònoma de Barcelona · ESInstitut de Nanociència i Nanotecnologia de la Universitat de BarcelonaUniversitat de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell death triggered by photodynamic therapy can occur through different mechanisms: apoptosis, necrosis or autophagy. However, recent studies have demonstrated the existence of other mechanisms with characteristics of both necrosis and apoptosis. These new cell death pathways, collectively termed regulated necrosis, include a variety of processes triggered by different stimuli. In this study, we evaluated the cell death mechanism induced by photodynamic treatments with two photosensitizers, meso-tetrakis (4-carboxyphenyl) porphyrin sodium salt (Na-H

Indexed as

ApoptosisPhotochemotherapyApoptosis Inducing FactorCaspase 3Cell Line, TumorCell MembraneCell Nucleus ShapeCell SurvivalCytotoxicity, ImmunologicEnzyme ActivationHumansInhibitory Concentration 50MetalloporphyrinsNecrosisNeoplasmsPhosphatidylserinesApoptosis Inducing FactorCaspase 3MetalloporphyrinsPhosphatidylserineszinc(II) tetrakis(4-carboxyphenyl)porphine

Identifiers

PMID28112275
PMCPMC5256096
OpenAlexW2581926397

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.