Evidence map›Paper›PMID 28112268›Full record

SynthesisScientific reports2017

Adherence to Mediterranean diet and risk of developing cognitive disorders: An updated systematic review and meta-analysis of prospective cohort studies.

Lei Wu, Dali Sun

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03614520 (Evaluation of Bioavailability and Metabolism of Diet Phenolic Compounds), which is not on this map. Cited by 95 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed, 14 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03614520 phase1completednot on this mapstarted 2018, after this paper: background citation

Evaluation of Bioavailability and Metabolism of Diet Phenolic Compounds

TypeinterventionalSponsorParc de Salut MarRan2018 to 2019Enrolled20ConditionsHealthyArmsAdministration of olive oil, Administration of red wine, Combination of red wine and olive oil, Water, Dark beer
3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 14 syntheses or guidelines pooled it.

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35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lei WuDepartment of Epidemiology, Institute of Geriatrics, Chinese People's Liberation Army General Hospital, Beijing, China.
Dali SunDepartment of Nanomedicine, Houston Methodist Research Institute, Houston, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent articles have presented inconsistent findings on the impact of Mediterranean diet in the occurrence of cognitive disorders; therefore, we performed an updated systematic review and meta-analysis to evaluate the potential association and dose-response pattern with accumulating evidence. We searched the PubMed and the Embase for the records relevant to this topic. A generic inverse-variance method was used to pool the outcome data for continuous variable, and categories of high vs. low, median vs. low of Mediterranean diet score with a random-effects model. Generalized least-squares trend estimation model was used to estimate the potential dose-response patterns of Mediterranean diet score on incident cognitive disorders. We identified 9 cohort studies involving 34,168 participants. Compared with the lowest category, the pooled analysis showed that the highest Mediterranean diet score was inversely associated with the developing of cognitive disorders, and the pooled RR (95% CI) was 0.79 (0.70, 0.90). Mediterranean diet score of the median category was not significantly associated with cognitive disorders. Dose-response analysis indicated a trend of an approximately linear relationship of the Mediterranean diet score with the incident risk of cognitive disorders. Further studies of randomized controlled trials are warranted to confirm the observed association in different populations.

Indexed as

Diet, MediterraneanPatient ComplianceAgedCognition DisordersConfidence IntervalsFemaleHumansMaleMiddle AgedProspective StudiesRisk Factors

Identifiers

PMID28112268
PMCPMC5256032

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.