Evidence map›Paper›PMID 28112192›Full record

ArticleScientific reports2017

STAC3 stably interacts through its C1 domain with Ca

Marta Campiglio, Bernhard E Flucher

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. CaHandbook of experimental pharmacology · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Skeletal muscle CaPflugers Archiv : European journal of physiology · 2020
    Review
  10. Review
  11. Crystal structures of CaProceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Duplex signaling by CaM and Stac3 enhances CaThe Journal of general physiology · 2018
    Article
  17. Article
  18. Article
  19. STAC proteins associate to the IQ domain of CaProceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  20. Dyadic Plasticity in Cardiomyocytes.Frontiers in physiology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Marta CampiglioDepartment of Physiology and Medical Physics, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Bernhard E FlucherDepartment of Physiology and Medical Physics, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Innsbruck Medical University · AT

Funding

Austrian Science Fund FWF P 27031Austrian Science Fund FWF T 855Austrian Science Fund FWF W 1101
6 · The paper itself

Abstract

The adaptor protein STAC3 is essential for skeletal muscle excitation-contraction (EC) coupling and a mutation in the STAC3 gene has been linked to a severe muscle disease, Native American myopathy (NAM). However the function of STAC3, its interaction partner, and the mode of interaction within the EC-coupling complex remained elusive. Here we demonstrate that STAC3 forms a stable interaction with the voltage-sensor of EC-coupling, Ca

Indexed as

Protein Interaction MappingAdaptor Proteins, Signal TransducingAnimalsDNA Mutational AnalysisLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsMiceMuscle, SkeletalNerve Tissue ProteinsProtein BindingRabbitsAdaptor Proteins, Signal TransducingLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsNerve Tissue ProteinsSTAC3 protein, mouse

Identifiers

PMID28112192
PMCPMC5253670
OpenAlexW2581645585

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.