ArticleBJU international2017
Detection of prostate cancer using magnetic resonance imaging/ultrasonography image-fusion targeted biopsy in African-American men.
Article in BJU international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 25 citations in OpenAlex.
- Is Prostate Imaging Reporting and Data System equally predictive across racial groups? A narrative review of multiparametric magnetic resonance imaging performance in Black versus White men.Prostate international · 2026Review
- Role of Systematic Biopsy in the Era of Targeted Biopsy: A Review.Current oncology (Toronto, Ont.) · 2024Review
- Defining the role of multiparametric MRI in predicting prostate cancer extracapsular extension.World journal of urology · 2024Article
- Why Does Magnetic Resonance Imaging-Targeted Biopsy Miss Clinically Significant Cancer?The Journal of urology · 2022Article
- Racial and Ethnic Disparities in the Use of Prostate Magnetic Resonance Imaging Following an Elevated Prostate-Specific Antigen Test.JAMA network open · 2021Article
- Northeastern Section of the American Urological Association 73rd Annual Meeting Abstracts.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2021Article
- Patient- and tumor-level risk factors for MRI-invisible prostate cancer.Prostate cancer and prostatic diseases · 2021Article
- Racial disparity in the utilization of multiparametric MRI-ultrasound fusion biopsy for the detection of prostate cancer.Prostate cancer and prostatic diseases · 2020Article
- Health disparities and inequities in the utilization of diagnostic imaging for prostate cancer.Abdominal radiology (New York) · 2020Review
- Rethinking active surveillance for prostate cancer in African American men.Translational andrology and urology · 2018Review
- Multiparametric MRI/ultrasound fusion-guided biopsy decreases detection of indolent cancer in African-American men.Prostate cancer and prostatic diseases · 2017Article
- African-American Prostate Cancer Disparities.Current urology reports · 2017Review
- The Contemporary Role of Multiparametric Magnetic Resonance Imaging in Active Surveillance for Prostate Cancer.Current urology reports · 2017Review
- A nomogram to predict the absence of clinically significant prostate cancer in males with negative MRIInternational braz j urol : official journal of the Brazilian Society of UrologyArticle
- Variation in Clinically Significant Prostate Cancer on Fusion Biopsy of PI-RADS 3-5 Lesions Based on Ethnicity.American journal of men's healthArticle
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
objectiveTo assess the diagnostic yield of targeted prostate biopsy in African-American (A-A) men using image fusion of multi-parametric magnetic resonance imaging (mpMRI) with real-time transrectal ultrasonography (US). PATIENTS AND
methodsWe retrospectively analysed 661 patients (117 A-A and 544 Caucasian) who had mpMRI before biopsy and then underwent MRI/US image-fusion targeted biopsy (FTB) between October 2012 and August 2015. The mpMRIs were reported on a 5-point Likert scale of suspicion. Clinically significant prostate cancer (CSPC) was defined as biopsy Gleason score ≥7.
resultsAfter controlling for age, prostate-specific antigen level and prostate volume, there were no significant differences between A-A and Caucasian men in the detection rate of overall cancer (35.0% vs 34.2%, P = 0.9) and CSPC (18.8% vs 21.7%, P = 0.3) with MRI/US FTB. There were no significant differences between the races in the location of dominant lesions on mpMRI, and in the proportion of 5-point Likert scoring. In A-A men, MRI/US FTB from the grade 4-5 lesions outperformed random biopsy in the detection rate of overall cancer (70.6% vs 37.2%, P = 0.003) and CSPC (52.9% vs 12.4%, P < 0.001). MRI/US FTB outperformed random biopsy in cancer core length (5.0 vs 2.4 mm, P = 0.001), in cancer rate per core (24.9% vs 6.8%, P < 0.001), and in efficiency for detecting one patient with CSPC (mean number of cores needed 13.3 vs 81.9, P < 0.001), respectively.
conclusionsOur key finding confirms a lack of racial difference in the detection rate of overall prostate cancers and CSPC with MRI/US FTB between A-A and Caucasian men. MRI/US FTB detected more CSPC using fewer cores compared with random biopsy.
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