Evidence map›Paper›PMID 28111633›Full record

ArticleCardiovascular regenerative medicine2016

MicroRNAs regulating meis1 expression and inducing cardiomyocyte proliferation.

Raghav Pandey, Yunhan Yang, Laeia Jackson, Rafeeq P H Ahmed

Open access · greenAbstract read
In one paragraph

Article in Cardiovascular regenerative medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Adult Cardiomyocyte Proliferation: a New Insight for Myocardial Infarction Therapy.Journal of cardiovascular translational research · 2021
    Review
  9. Review
  10. Review
  11. Homeobox gene Meis1 modulates cardiovascular regeneration.Seminars in cell & developmental biology · 2020
    Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Raghav PandeyDepartment of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati OH, 45267, USA.
Yunhan YangDepartment of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati OH, 45267, USA.
Laeia JacksonMeharry Medical College, Nashville TN, 37208, USA.
Rafeeq P H AhmedDepartment of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati OH, 45267, USA.
University of Cincinnati Medical Center · USMeharry Medical College · US

Funding

Angiomyogenesis with HIF-1a responsive microRNAsR01HL106190 · NHLBI · UNIVERSITY OF CINCINNATI · PI HABEEBAHMED, RAFEEQ · 2011 to 2016
$2.8M
NHLBI NIH HHS R01 HL106190
6 · The paper itself

Abstract

Cardiovascular disease has been the biggest killer in the United States for decades, with almost a million new cases each year. Even though mammalian rodent neonatal cardiomyocytes show proliferative potential for up to 5 days, adult cardiomyocytes lose this ability. Insufficient cardiomyocyte proliferation is one of the major reasons for the lack of regeneration of myocardial tissue, post injury. Several studies have looked at the mechanisms responsible for the arrest in proliferation at an adult stage. Following up on a recent study by Eulalio

Indexed as

Adult CardiomyocytesCardiac regenerationCardiomyocyte ProliferationMeis1miR-23bmiR-509miR-548c

Identifiers

PMID28111633
PMCPMC5245919
OpenAlexW2583286401

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.