Evidence map›Paper›PMID 28111553›Full record

ArticleFrontiers in physiology2016

Retinoic Acid Excess Impairs Amelogenesis Inducing Enamel Defects.

Supawich Morkmued, Virginie Laugel-Haushalter, Eric Mathieu, Brigitte Schuhbaur, Joseph Hemmerlé, Pascal Dollé, Agnès Bloch-Zupan, Karen Niederreither

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Supawich MorkmuedDevelopmental Biology and Stem Cells Department, Institute of Genetics and Molecular and Cellular Biology (IGBMC)Illkirch, France; Centre National de la Recherche Scientifique, UMR 7104Illkirch, France; Institut National de la Santé et de la Recherche Médicale, U 964Illkirch, France; Université de StrasbourgIllkirch, France; Pediatrics Department, Faculty of Dentistry, Khon Kaen UniversityKhon Kaen, Thailand.
Virginie Laugel-HaushalterDevelopmental Biology and Stem Cells Department, Institute of Genetics and Molecular and Cellular Biology (IGBMC)Illkirch, France; Centre National de la Recherche Scientifique, UMR 7104Illkirch, France; Institut National de la Santé et de la Recherche Médicale, U 964Illkirch, France; Université de StrasbourgIllkirch, France.
Eric MathieuUniversité de Strasbourg, INSERM UMR_1121, Biomaterials and Bioengineering Strasbourg, France.
Brigitte SchuhbaurDevelopmental Biology and Stem Cells Department, Institute of Genetics and Molecular and Cellular Biology (IGBMC)Illkirch, France; Centre National de la Recherche Scientifique, UMR 7104Illkirch, France; Institut National de la Santé et de la Recherche Médicale, U 964Illkirch, France; Université de StrasbourgIllkirch, France.
Joseph HemmerléUniversité de Strasbourg, INSERM UMR_1121, Biomaterials and Bioengineering Strasbourg, France.
Pascal DolléDevelopmental Biology and Stem Cells Department, Institute of Genetics and Molecular and Cellular Biology (IGBMC)Illkirch, France; Centre National de la Recherche Scientifique, UMR 7104Illkirch, France; Institut National de la Santé et de la Recherche Médicale, U 964Illkirch, France; Université de StrasbourgIllkirch, France.
Agnès Bloch-ZupanDevelopmental Biology and Stem Cells Department, Institute of Genetics and Molecular and Cellular Biology (IGBMC)Illkirch, France; Centre National de la Recherche Scientifique, UMR 7104Illkirch, France; Institut National de la Santé et de la Recherche Médicale, U 964Illkirch, France; Université de StrasbourgIllkirch, France; Faculté de Chirurgie Dentaire, Université de StrasbourgStrasbourg, France; Faculté de Médecine, Fédération de Médecine Translationnelle de Strasbourg, Université de StrasbourgStrasbourg, France; Hôpitaux Universitaires de Strasbourg, Pôle de Médecine et Chirurgie Bucco-Dentaires, Centre de Référence des Manifestations Odontologiques des Maladies Rares, CRMRStrasbourg, France; Eastman Dental Institute, University College LondonLondon, UK.
Karen NiederreitherDevelopmental Biology and Stem Cells Department, Institute of Genetics and Molecular and Cellular Biology (IGBMC)Illkirch, France; Centre National de la Recherche Scientifique, UMR 7104Illkirch, France; Institut National de la Santé et de la Recherche Médicale, U 964Illkirch, France; Université de StrasbourgIllkirch, France; Faculté de Chirurgie Dentaire, Université de StrasbourgStrasbourg, France.
Inserm · FRInstitut de génétique et de biologie moléculaire et cellulaire · FRHôpitaux Universitaires de Strasbourg · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abnormalities of enamel matrix proteins deposition, mineralization, or degradation during tooth development are responsible for a spectrum of either genetic diseases termed

Indexed as

enamelenamelinmouse modelsretinoidsRNA-seqtooth

Identifiers

PMID28111553
PMCPMC5217128
OpenAlexW2570883143

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.