Evidence map›Paper›PMID 28111468›Full record

ArticleLeukemia2017

Deletion of Ptpn1 induces myeloproliferative neoplasm.

F Jobe, B Patel, T Kuzmanovic, H Makishima, Y Yang, B Przychodzen, R E Hutchison, K K Bence, J P Maciejewski, G Mohi

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Leukemia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

F JobeDepartment of Pharmacology, SUNY Upstate Medical University, Syracuse, NY, USA.
B PatelDepartment of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.
T KuzmanovicDepartment of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.
H MakishimaDepartment of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.
Y YangDepartment of Pharmacology, SUNY Upstate Medical University, Syracuse, NY, USA.
B PrzychodzenDepartment of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.
R E HutchisonDepartment of Pathology, SUNY Upstate Medical University, Syracuse, NY, USA.
K K BenceDepartment of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.
J P MaciejewskiDepartment of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.
G MohiDepartment of Pharmacology, SUNY Upstate Medical University, Syracuse, NY, USA.
Cleveland Clinic · USSUNY Upstate Medical University · USUniversity of Pennsylvania · US

Funding

Role of JAK2V617F in the Pathogenesis of Myeloproliferative NeoplasmsR01HL095685 · NHLBI · UPSTATE MEDICAL UNIVERSITY · PI MOHI, GOLAM · 2009 to 2018
$3.8M
Predisposition to chromosomal alterations in MDSR01HL082983 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI MACIEJEWSKI, JAROSLAW P. · 2005 to 2008
$1.5M
TCR Diagnostics in LGL Leukemia and Immune CytopeniasR01CA113972 · NCI · CLEVELAND CLINIC LERNER COM-CWRU · PI MACIEJEWSKI, JAROSLAW P. · 2005 to 2009
$1.5M
Role of PTPN1 in myeloid malignanciesR21CA187128 · NCI · UPSTATE MEDICAL UNIVERSITY · PI MOHI, GOLAM · 2015 to 2017
$386k
LASER SCANNING CONFOCAL MICROSCOPE: NEUROSCIENCES10RR019391 · NCRR · UNIVERSITY OF LOUISVILLE · PI EPSTEIN, PAUL N. · 2004 to 2004
$315k
NCI NIH HHS R01 CA113972NCI NIH HHS R21 CA187128NCRR NIH HHS S10 RR019391NHLBI NIH HHS R01 HL082983NHLBI NIH HHS R01 HL095685
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene DeletionAnimalsChromosomes, Human, Pair 20Cohort StudiesFlow CytometryHematologic NeoplasmsHumansIn Situ Hybridization, FluorescenceMiceMice, KnockoutMyeloproliferative DisordersProtein Tyrosine Phosphatase, Non-Receptor Type 1Protein Tyrosine Phosphatase, Non-Receptor Type 1PTPN1 protein, human

Identifiers

PMID28111468
PMCPMC5967380
OpenAlexW2580054209

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.