ArticleThe Journal of urology2017
Temporal Changes in Kidney Stone Composition and in Risk Factors Predisposing to Stone Formation.
Article in The Journal of urology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.
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Who cites it
34 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Vascular calcification on the risk of kidney stone: a meta-analysis.Renal failure · 2023Pooled it
- Macrophage Function in Calcium Oxalate Kidney Stone Formation: A Systematic Review of Literature.Frontiers in immunology · 2021Pooled it
- The impact of body mass index on quantitative 24-h urine chemistries in stone forming patients: a systematic review and meta-analysis.Urolithiasis · 2018Pooled it
- Increased production and reduced urinary buffering of acid in uric acid stone formers is ameliorated by pioglitazone.Kidney international · 2019Trial
- Acute Effect of High Fat Intake on Urinary Acidification Parameters.Kidney international reports · 2025Article
- High Fat Intake: A Dietary Consideration for Uric Acid Nephrolithiasis?Kidney international reports · 2025Article
- Article
- The clinical efficacy of novel semirigid ureteroscopy with a vacuum suction device for treatment of >10 mm upper ureteral stones and impacted calculus: implications for clinical practice.Frontiers in surgery · 2025Article
- Complications of Single-Use Flexible Ureteroscopy vs. Reusable Flexible Ureteroscopy: A Narrative Review.Cureus · 2024Review
- A nomogram to predict "pure" vs. "mixed" uric acid urinary stones.World journal of urology · 2024Article
- Radiomics and Clinical Features for Distinguishing Kidney Stone-Associated Urinary Tract Infection: A Comprehensive Analysis of Machine Learning Classification.Open forum infectious diseases · 2024Article
- Review
- Pathophysiology and Main Molecular Mechanisms of Urinary Stone Formation and Recurrence.International journal of molecular sciences · 2024Review
- The SOX4/EZH2/SLC7A11 signaling axis mediates ferroptosis in calcium oxalate crystal deposition-induced kidney injury.Journal of translational medicine · 2024Article
- Combined semirigid and flexible ureterorenoscopy for the treatment of large renal stones.Journal of medicine and life · 2023Article
- Epidemiology of Kidney Stones.Healthcare (Basel, Switzerland) · 2023Review
- Integrated analysis of mRNA-seq and miRNA-seq reveals the potential roles of Egr1, Rxra and Max in kidney stone disease.Urolithiasis · 2022Article
- NO Residual Stones after Flexible Ureteroscopy for Renal Stones - Update 2021. A Narrative Brief Review.Maedica · 2022Article
- Role of insulin resistance and the gut microbiome on urine oxalate excretion in ob/ob mice.Physiological reports · 2022Article
- Atorvastatin Decreases Renal Calcium Oxalate Stone Deposits by Enhancing Renal Osteopontin Expression in Hyperoxaluric Stone-Forming Rats Fed a High-Fat Diet.International journal of molecular sciences · 2022Article
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Authors and funding
6 authors.
Funding
Abstract
purposeThe prevalence of kidney stones has increased globally in recent decades. However, studies investigating the association between temporal changes in the risk of stone formation and stone types are scarce. We investigated temporal changes in stone composition, and demographic, serum and urinary parameters of kidney stone formers from 1980 to 2015. MATERIALS AND
methodsWe retrospectively analyzed the records of 1,516 patients diagnosed with either calcium or uric acid stones at an initial visit to a university kidney stone clinic from 1980 to 2015.
resultsFrom 1980 to 2015, the proportion of uric acid stones in all stone formers increased from 7% to 14%. While age and body mass index increased with time in both uric acid and calcium stone formers, uric acid stone formers were consistently older and had a higher body mass index and lower urinary pH than calcium stone formers. The proportion of females with stones has increased over time but the increase in female gender was more prominent among calcium stone formers. Urinary pH, phosphorus, oxalate and sodium increased with time in calcium stone formers but remained unchanged in uric acid stone formers. After accounting for various parameters of stone risk, the strongest clinical discriminant of uric acid vs calcium stones was urinary pH. Limitations of this study include the retrospective single center design and the available number of patients with stone analysis.
conclusionsFrom 1980 to 2015, the proportion of uric acid stones increased significantly. With time, there were proportionately more female calcium stone formers but not uric acid stone formers. Urinary pH is the most prominent factor distinguishing uric acid from calcium stones.
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