Evidence map›Paper›PMID 28111191›Full record

ArticleInsect biochemistry and molecular biology2017

Mutations of two acidic residues at the cytoplasmic end of segment IIIS6 of an insect sodium channel have distinct effects on pyrethroid resistance.

Mengli Chen, Yuzhe Du, Yoshiko Nomura, Guonian Zhu, Boris S Zhorov, Ke Dong

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Insect biochemistry and molecular biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 4 countries.

Mengli ChenInstitute of Pesticide and Environmental Toxicology, Zhejiang University, Hangzhou 310029, China; Department of Entomology, Genetics and Neuroscience Programs, Michigan State University, East Lansing, MI48824, USA.
Yuzhe DuDepartment of Entomology, Genetics and Neuroscience Programs, Michigan State University, East Lansing, MI48824, USA.
Yoshiko NomuraDepartment of Entomology, Genetics and Neuroscience Programs, Michigan State University, East Lansing, MI48824, USA.
Guonian ZhuInstitute of Pesticide and Environmental Toxicology, Zhejiang University, Hangzhou 310029, China.
Boris S ZhorovDepartment of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario L8N 3Z5, Canada; Sechenov Institute of Evolutionary Physiology & Biochemistry, Russian Academy of Sciences, St. Petersburg 194223, Russia.
Ke DongDepartment of Entomology, Genetics and Neuroscience Programs, Michigan State University, East Lansing, MI48824, USA. Electronic address: dongk@cns.msu.edu.
Michigan State University · USInstitute of Evolutionary Physiology and Biochemistry · RUZhejiang University · CN

Funding

Molecular mechanisms of action and resistance of sodium channel-targeting insectiR01GM057440 · NIGMS · MICHIGAN STATE UNIVERSITY · PI DONG, KE, HUGHSON, FREDERICK M · 1999 to 2023
$5.4M
NIGMS NIH HHS R01 GM057440
6 · The paper itself

Abstract

Mutations in sodium channels are known to confer knockdown resistance to pyrethroid insecticides, such as permethrin and cypermethrin, in various agricultural pests and disease vectors. Double mutations, D

Indexed as

InsecticidesPyrethrinsAnimalsBlattellidaeInsecticide ResistanceInsect ProteinsMutationSodium ChannelsXenopusInsecticidesInsect ProteinsPyrethrinsSodium ChannelsKnockdown resistancePyrethroid receptorSodium channelType II pyrethroidsType I pyrethroids

Identifiers

PMID28111191
PMCPMC5730327
OpenAlexW2575649910

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.