Evidence map›Paper›PMID 28111077›Full record

ArticleNeuron2017

Synaptotagmin-1- and Synaptotagmin-7-Dependent Fusion Mechanisms Target Synaptic Vesicles to Kinetically Distinct Endocytic Pathways.

Ying C Li, Natali L Chanaday, Wei Xu, Ege T Kavalali

Open access · bronzeAbstract read
In one paragraph

Article in Neuron, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 101 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Identifying Key Regulators in Odorant Receptor Trafficking.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Complexin has a dual synaptic function as checkpoint protein in vesicle priming and as a promoter of vesicle fusion.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  14. Spatially non-overlapping CaCell reports · 2023
    Article
  15. Synaptotagmin-11 Inhibits Synaptic Vesicle Endocytosis via Endophilin A1.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  16. Article
  17. Calcium Sensors of Neurotransmitter Release.Advances in neurobiology · 2023
    Article
  18. Genetic disorders of neurotransmitter release machinery.Frontiers in synaptic neuroscience · 2023
    Review
  19. Review
  20. Synaptotagmin-1 is a bidirectional CaProceedings of the National Academy of Sciences of the United States of America · 2022
    Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ying C LiDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390-9111, USA.
Natali L ChanadayDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390-9111, USA.
Wei XuDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390-9111, USA.
Ege T KavalaliDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390-9111, USA. Electronic address: ege.kavalali@utsouthwestern.edu.
The University of Texas Southwestern Medical Center · US

Funding

Role of SNARE Interactions in Central Synapse FunctionR01MH066198 · NIMH · VANDERBILT UNIVERSITY · PI KAVALALI, EGE T · 2004 to 2023
$7.9M
NIMH NIH HHS R01 MH066198
6 · The paper itself

Abstract

Synaptic vesicle recycling is essential for maintaining normal synaptic function. The coupling of exocytosis and endocytosis is assumed to be Ca

Indexed as

Action PotentialsAdaptor Proteins, Vesicular TransportAnimalsBlotting, WesternCalciumEndocytosisGene Knockdown TechniquesHippocampusMembrane FusionNerve Tissue ProteinsNeuronsPatch-Clamp TechniquesRatsSynaptic VesiclesSynaptotagmin ISynaptotagminsAdaptor Proteins, Vesicular TransportCalciumcomplexin Icomplexin IINerve Tissue ProteinsSynaptotagmin ISynaptotagminsasynchronous releasecalcium regulation of endocytosiscomplexinendocytosissingle-vesicle imagingsynaptic vesicle endocytosissynaptic vesicle recyclingsynaptotagmin-1synaptotagmin-7synchronous release

Identifiers

PMID28111077
PMCPMC5300960
OpenAlexW2572503237

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.