Evidence map›Paper›PMID 28111062›Full record

ArticleThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2017

Psychotropic Medication Use among Medicare Beneficiaries Following Traumatic Brain Injury.

Jennifer S Albrecht, Daniel C Mullins, Gordon S Smith, Vani Rao

Open access · greenAbstract read
In one paragraph

Article in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
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  6. Treatment Patterns of Anxiety and Posttraumatic Stress Disorder Following Traumatic Brain Injury.The Journal of neuropsychiatry and clinical neurosciences · 2022
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  11. Successful Treatment of Psychiatric Symptoms after Traumatic Brain Injury Using Deep Brain Stimulation to the Anterior Limb of Internal Capsule-Nucleus Accumbens.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jennifer S AlbrechtDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD. Electronic address: jalbrecht@epi.umaryland.edu.
Daniel C MullinsDepartment of Pharmaceutical Health Services Research, University of Maryland School of Pharmacy, Baltimore, MD.
Gordon S SmithDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD; Shock, Trauma and Anesthesiology Research-Organized Research Center, National Study Center for Trauma and Emergency Medical Services, University of Maryland, Baltimore, MD.
Vani RaoDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD.
University of Maryland, Baltimore · USJohns Hopkins University · US

Funding

West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Sally Lynn Hodder · 2012 to 2026
$81.0M
Hangovers and Traffic Injuries: Is Alcohol's Influence Greater Than Expected?R01AA018313 · NIAAA · UNIVERSITY OF MARYLAND BALTIMORE · PI SMITH, GORDON STEPHEN · 2010 to 2014
$2.7M
Alcohol Involvement in a Cohort of Trauma Patients: Trends and Future MortalityR01AA018707 · NIAAA · UNIVERSITY OF MARYLAND BALTIMORE · PI SMITH, GORDON STEPHEN · 2010 to 2014
$1.5M
Prioritizing Quality Improvement for the Treatment of Psychiatric Disturbances Following Traumatic Brain InjuryK01HS024560 · AHRQ · UNIVERSITY OF MARYLAND BALTIMORE · PI ALBRECHT, JENNIFER S. · 2016 to 2020
$735k
AHRQ HHS K01 HS024560NIAAA NIH HHS R01 AA018313NIAAA NIH HHS R01 AA018707NIGMS NIH HHS U54 GM104942
6 · The paper itself

Abstract

objectivesTo characterize psychotropic medication use before and after traumatic brain injury (TBI) hospitalization among older adults. A secondary objective is to determine how receipt of indicated pharmacologic treatment for anxiety and post-traumatic stress disorder (PTSD) differs following TBI.

designRetrospective cohort.

settingUnited States.

participantsMedicare beneficiaries aged ≥65 years hospitalized with TBI between 2006 and 2010 with continuous drug coverage for 12 months before and after TBI (N = 60,276). MEASUREMENTS: We obtained monthly psychotropic medication use by drug class and specific drugs from Medicare Part D drug event files.ICD-9 codes were used to define anxiety (300.0x) and PTSD (309.81).

resultsAverage monthly prevalence of psychotropic medication use among all patients hospitalized for TBI was 44.8%; antidepressants constituted 73%. Prevalence of psychotropic medication use increased from 2006 to 2010. Following TBI, psychotropic medication use increased slightly (OR: 1.05; 95% CI: 1.03, 1.06.) Tricyclic antidepressant use decreased post-TBI (OR: 0.76; 95% CI: 0.73, 0.79) whereas use of the sedating antidepressants mirtazapine (OR: 1.31; 95% CI: 1.25, 1.37) and trazadone (OR: 1.11; 95% CI: 1.06, 1.17) increased. Antipsychotic (OR: 1.15; 95% CI: 1.12, 1.19) use also increased post-TBI. Beneficiaries newly diagnosed with anxiety (OR: 0.42; 95% CI: 0.36, 0.48) and/or PTSD (OR: 0.39; 95% CI: 0.18, 0.84) post-TBI were less likely to receive indicated pharmacologic treatment.

conclusionsOlder adults hospitalized with TBI have a high prevalence of psychotropic medication use yet are less likely to receive indicated pharmacological treatment for newly diagnosed anxiety and PTSD following TBI.

Indexed as

AgedAged, 80 and overAntidepressive AgentsAntipsychotic AgentsAnxietyBrain Injuries, TraumaticComorbidityFemaleHospitalizationHumansMaleMedicarePsychotropic DrugsStress Disorders, Post-TraumaticUnited StatesAntidepressive AgentsAntipsychotic AgentsPsychotropic Drugsneuropsychiatric disordersolder adultspsychotropic medicationsTraumatic brain injury

Identifiers

PMID28111062
PMCPMC5365362
OpenAlexW2565883851

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.