Evidence map›Paper›PMID 28110383›Full record

SynthesisInternational journal of colorectal disease2017

Risk factors for recurrence after acute colonic diverticulitis: a systematic review.

Line Hupfeld, Jakob Burcharth, Hans-Christian Pommergaard, Jacob Rosenberg

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in International journal of colorectal disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 5 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 5 syntheses or guidelines pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Antibiotics for uncomplicated diverticulitis.The Cochrane database of systematic reviews · 2022
    Pooled it
  5. Pooled it
  6. Trial
  7. Trial
  8. Trial
  9. Natural Language Processing Algorithm Accurately Classifies Diverticulitis-Related Complications and Predicts Long-Term Outcomes.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2026
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Surgery for young onset diverticulitis: is it curative?International journal of colorectal disease · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. [Indications for surgical treatment of diverticular disease].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Line HupfeldDepartment of Surgery, Herlev Hospital, University of Copenhagen, Herlev, Denmark. linehupfeld01@gmail.com.ORCID http://orcid.org/0000-0002-5865-2939
Jakob BurcharthDepartment of Surgery, Zealand University Hospital, University of Copenhagen, Køge, Denmark.
Hans-Christian PommergaardDepartment of Surgical Gastroenterology, Rigshospitalet, University of Copenhagen, Copenhagen, Danmark.
Jacob RosenbergDepartment of Surgery, Herlev Hospital, University of Copenhagen, Herlev, Denmark.
University of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSeveral factors may influence the risk of recurrence after an episode of acute colonic diverticulitis. Until now, a comprehensive systematic overview and evaluation of relevant risk factors have not been presented. This review aimed at assembling and evaluating current evidence on risk factors for recurrence after conservatively treated acute colonic diverticulitis.

methodsPubMed, Embase, and Cochrane databases were searched for studies evaluating risk factors for recurrence after acute diverticulitis treated non-surgically defined as antibiotic treatment, percutaneous abscess drainage, or by observation. Randomized clinical trials and observational studies were included. Analyzed outcome variables were extracted and grouped. No meta-analysis was performed due to low inter-study comparability. Variables were rated according to their likelihood of causing recurrence (no/low, medium, high).

resultsOf 1153 screened records, 35 studies were included, enrolling 396,676 patients with acute diverticulitis. A total of 50,555 patients experienced recurrences. Primary diverticulitis with abscess formation and young age increased the risk of recurrence. Readmission risk was higher within the first year after remission. In addition, the risk of subsequent diverticulitis more than doubled after two earlier episodes of diverticulitis and the risk increased further for every episode.

conclusionsThe best treatment strategy for recurrent diverticulitis is undetermined. However, the risk of a new recurrence seemed to increase after each recurrence making elective resection a viable option at some point after multiple recurrences depending on patient risk factors and preferences.

Indexed as

AbscessAcute DiseaseAdultAgedBody Mass IndexDiverticulitis, ColonicFemaleHumansInflammationMaleMiddle AgedRecurrenceRisk FactorsTime FactorsAcute diverticulitisReadmissionRecurrenceRisk factors

Identifiers

PMID28110383
OpenAlexW2571876191

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.