Evidence map›Paper›PMID 28110088›Full record

ArticleNeuroImage2017

Regional and source-based patterns of [

Patrick D Worhunsky, David Matuskey, Jean-Dominique Gallezot, Edward C Gaiser, Nabeel Nabulsi, Gustavo A Angarita, Vince D Calhoun, Robert T Malison, Marc N Potenza, Richard E Carson

Registry-linked trialAbstract read
In one paragraph

Article in NeuroImage, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05105542 (Muscarinic M1 Receptor Availability and Cognition in Schizophrenia), which is not on this map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05105542 phase1completednot on this mapstarted 2021, after this paper: background citation

Muscarinic M1 Receptor Availability and Cognition in Schizophrenia

TypeinterventionalSponsorYale UniversityRan2021 to 2023Enrolled18ConditionsSchizophrenia, Schizoaffective Disorder, HealthyArms11C-EMO - A Novel PET Radiotracer for Muscarinic M1 Receptor, PET Scan
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 43 citations in OpenAlex.

  1. Trial
  2. Article
  3. Molecular connectivity studies in neurotransmission: a scoping review.Imaging neuroscience (Cambridge, Mass.) · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Dopamine DDrug and alcohol dependence · 2021
    Article
  17. Multimodal investigation of dopamine DNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021
    Article
  18. Association of dopamine DNeuroImage · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Patrick D WorhunskyDepartment of Radiology & Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA. Electronic address: patrick.worhunsky@yale.edu.
David MatuskeyDepartment of Radiology & Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.
Jean-Dominique GallezotDepartment of Radiology & Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.
Edward C GaiserDepartment of Radiology & Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.
Nabeel NabulsiDepartment of Radiology & Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.
Gustavo A AngaritaDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA.
Vince D CalhounDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA; Department of Electrical & Computer Engineering, University of New Mexico, Albuquerque, NM, USA; The Mind Research Network, Albuquerque, NM, USA.
Robert T MalisonDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA.
Marc N PotenzaDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA; Child Study Center, Yale School of Medicine, New Haven, CT, USA; Department of Neuroscience, Yale School of Medicine, New Haven, CT, USA; National Center on Addiction and Substance Abuse, Yale School of Medicine, New Haven, CT, USA.
Richard E CarsonDepartment of Radiology & Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.
Yale University · USUniversity of New Mexico · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale University Clinical and Translational Science Award ProgramUL1TR000142 · NCATS · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2012 to 2015
$31.8M
SUBSTANCE ABUSEK12DA000167 · NIDA · YALE UNIVERSITY · PI STEPHANIE S O'MALLEY, Marc N Potenza · 1991 to 2026
$17.7M
Transcranial Direct Current Stimulation for Treatment of Auditory Verbal HalluciP20GM103472 · NIGMS · THE MIND RESEARCH NETWORK · PI THOMA, ROBERT J · 2012 to 2017
$14.3M
Multivariate methods for identifying multitask/multimodal brain imaging biomarkersR01EB006841 · NIBIB · THE MIND RESEARCH NETWORK · PI VINCE D CALHOUN, Sergey Plis · 2007 to 2026
$9.8M
Neuroimaging Sciences Training ProgramT32DA022975 · NIDA · YALE UNIVERSITY · PI Graeme F Mason, Rajita Sinha · 2007 to 2026
$5.7M
Informed Data-Driven Fusion of Behavior, Brain Function, and GenesR01EB005846 · NIBIB · THE MIND RESEARCH NETWORK · PI CALHOUN, VINCE D · 2005 to 2016
$5.5M
Translational Research of Cocaine, Striatum, and ImpulsivitiesP20DA027844 · NIDA · YALE UNIVERSITY · PI POTENZA, MARC N · 2010 to 2013
$3.6M
Unified multivariate data-driven solutions for static and dynamic brain connectivityR01EB020407 · NIBIB · THE MIND RESEARCH NETWORK · PI ADALI, TULAY, CALHOUN, VINCE D · 2015 to 2018
$2.7M
Functional networks related to cocaine dependence and its treatment and relapseR01DA039136 · NIDA · YALE UNIVERSITY · PI POTENZA, MARC N · 2016 to 2018
$754k
DBH, D2High and Cocaine Paranoia/Aversion: A [11C]PHNO PET StudyR03DA027456 · NIDA · YALE UNIVERSITY · PI MALISON, ROBERT T · 2009 to 2010
$420k
NCATS NIH HHS UL1 TR000142NCATS NIH HHS UL1 TR001863NIBIB NIH HHS R01 EB005846NIBIB NIH HHS R01 EB006841NIBIB NIH HHS R01 EB020407NIDA NIH HHS K12 DA000167NIDA NIH HHS P20 DA027844NIDA NIH HHS R01 DA039136NIDA NIH HHS R03 DA027456NIDA NIH HHS T32 DA022975NIGMS NIH HHS P20 GM103472
6 · The paper itself

Abstract

Dopamine type 2 and type 3 receptors (D

Indexed as

AdultBrainBrain MappingCocaine-Related DisordersDisease ProgressionDopamine AgentsFemaleHumansImage Processing, Computer-AssistedMaleMiddle AgedOxazinesPositron-Emission TomographyRadiopharmaceuticalsReceptors, Dopamine D2Receptors, Dopamine D3Dopamine AgentsDRD2 protein, humanDRD3 protein, humannaxagolideOxazinesRadiopharmaceuticalsReceptors, Dopamine D2Receptors, Dopamine D3[(11)C]-(+)-PHNOAddictionCocaine use disorderDopamineIndependent component analysisStriatum

Identifiers

PMID28110088
PMCPMC5344702
OpenAlexW2572571751

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.