ArticleThe Science of the total environment2017
Mapping sites of high TB transmission risk: Integrating the shared air and social behaviour of TB cases and adolescents in a South African township.
Article in The Science of the total environment, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Contact tracing strategies in household and congregate environments to identify cases of tuberculosis in low- and moderate-incidence populations.The Cochrane database of systematic reviews · 2019Pooled it
- Methods used in the spatial analysis of tuberculosis epidemiology: a systematic review.BMC medicine · 2018Pooled it
- Risk Factors for Immunological Sensitization to Mycobacterium tuberculosis and Progression to Incident TB Disease Among HIV-uninfected Adults in a High Burden Setting.The Journal of infectious diseases · 2026Article
- Drivers of sex differences in Mycobacterium tuberculosis immunoreactivity among adolescents and adults in Blantyre, Malawi.BMC global and public health · 2026Article
- Understanding the relationship between adolescents with tuberculosis and health services: an indepth qualitative study from Cape Town.BMJ open · 2025Observational
- Mobility patterns, activity locations, and TB in Nairobi, Kenya.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2025Article
- Drug-Resistant Tuberculosis Hotspots in Oliver Reginald Tambo District Municipality, Eastern Cape, South Africa.Infectious disease reports · 2024Article
- Article
- Article
- Finding and treating both tuberculosis disease and latent infection during population-wide active case finding for tuberculosis elimination.Frontiers in medicine · 2023Review
- Zonal modeling of air distribution impact on the long-range airborne transmission risk of SARS-CoV-2.Applied mathematical modelling · 2022Article
- Review
- Importance of ventilation and occupancy to Mycobacterium tuberculosis transmission rates in congregate settings.BMC public health · 2022Article
- Modeling the impact of indoor relative humidity on the infection risk of five respiratory airborne viruses.Scientific reports · 2022Article
- Tuberculosis in Adolescents and Young Adults: Emerging Data on TB Transmission and Prevention among Vulnerable Young People.Tropical medicine and infectious disease · 2021Review
- Spatial drivers of COVID-19 vulnerability in Nigeria.The Pan African medical journal · 2021Article
- Unfavorable Outcomes in Tuberculosis: Multidimensional Factors among Adolescents in Rio de Janeiro, Brazil.The American journal of tropical medicine and hygiene · 2020Article
- Resource reprioritisation amid competing health risks for TB and COVID-19.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2020Article
- Performance of a household tuberculosis exposure survey among children in a Latin American setting.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2019Article
- Intervening along the spectrum of tuberculosis: meeting report from the World TB Day nanosymposium in the Institute of Infectious Disease and Molecular Medicine at the University of Cape Town.Gates open research · 2019Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTuberculosis remains a major public health problem in poverty-stricken areas of the world. Communal gathering places account for the majority of TB transmission in high burden settings.
objectiveTo investigate the social behaviour patterns of individuals who have developed TB disease and adolescents at risk of infection. To develop a cheap and effective method to locate transmission hot spots in high burden communities.
designPortable, combined CO
resultsAnalysis of diaries found that the adolescent group spent greater time in congregate settings compared with the other two groups driven by time spent in school/work (new TB: 1%, recent TB: 8%, and adolescents: 23%). Adolescents also changed their location more frequently (9.0, 6.0, 14.3 changes per day; p<0.001). The RAVs reflected this divergence between the groups (44, 40, 127l; p<0.001). Communal buildings associated with high RAVs were found to be a clinic, two schools and a library. Hot spot analysis revealed the most intense clustering of high RAVs at a community school.
conclusionOur study demonstrates a new methodology to uncover TB transmission hot spots using a technique that avoids the need to pre-select locations. Investigation of a South African township highlighted the high risk potential of schools and high risk social behaviour of adolescents. Consequently the targeting of transmission reduction strategies to schools may prove highly efficacious in high burden settings.
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