ArticleOral oncology2017
Depression and survival in head and neck cancer patients.
Article in Oral oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05724849 (Venlafaxine for the Prevention of Depression in Patients With Head and Neck Cancer), which is not on this map. Cited by 70 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Venlafaxine for the Prevention of Depression in Patients With Head and Neck Cancer
Who cites it
70 citing papers in PubMed, 4 syntheses or guidelines pooled it, 135 citations in OpenAlex.
- Development of depression in patients with oropharyngeal cancer: a systematic review.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2026Pooled it
- Evidence-based guideline diagnosis, treatment, prevention and aftercare of oropharyngeal and hypopharyngeal carcinoma.German medical science : GMS e-journal · 2025Guideline
- Psychological Factors Related to Treatment Outcomes in Head and Neck Cancer.Advances in therapy · 2024Pooled it
- Major Depression and Survival in People With Cancer.Psychosomatic medicine · 2021Pooled it
- Mindfulness-Based Stress Reduction Alleviates Depression, Anxiety, and Internalized Stigma Compared With Treatment-as-Usual Among Head and Neck Cancer Patients: Findings From a Randomized Controlled Trial.Depression and anxiety · 2025Trial
- De-Novo Depression, Prophylactic Antidepressant, and Survival in Patients With Head and Neck Cancer.The Laryngoscope · 2023Trial
- Associations Between Preexisting Depression and Anxiety and Postoperative Outcomes Among Medicare Beneficiaries Undergoing Head and Neck Cancer Surgery.Head & neck · 2026Article
- Mental Health and Survival in Medicare Beneficiaries With Lung and Head and Neck Cancer.Psycho-oncology · 2026Article
- Missed Clinic Appointments for Human Papillomavirus-Related Oropharyngeal Cancer.Laryngoscope investigative otolaryngology · 2026Article
- The Self-Perpetuating Cycle of Psychological Distress and Clinical Outcomes in Head and Neck Oncology.Cancers · 2026Review
- Out-of-Pocket Costs and Antidepressant Adherence in Head and Neck Cancer Survivors.Psycho-oncology · 2026Article
- Article
- Oral cancer in women: clinical profile, risk factors, treatment outcomes and survival predictors in 32 years of experience.Clinical oral investigations · 2025Article
- Low resilience in patients with cancer as a factor influencing anxiety, depression, and quality-of-life.World journal of psychiatry · 2025Article
- Availability and Characteristics of Support Groups for People With Head and Neck Cancer in Australia.Asia-Pacific journal of clinical oncology · 2025Article
- Pre-radiotherapy multidisciplinary survivorship care and patient-reported outcomes in head and neck cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- The mediating role of resilience in the relationships between posttraumatic growth and depression as well as anxiety among survivors of nasopharyngeal carcinoma: a cross-sectional study.BMC psychology · 2025Article
- Demographic Disparities in Diagnosis and Treatment of Anxiety and Depressive Disorders in Head and Neck Cancer Survivors.Head & neck · 2025Article
- Psychological distress of patients with head and neck cancer following various oncologic treatments-A longitudinal study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Nutrition in head and neck cancer care: a roadmap and call for research.The Lancet. Oncology · 2025Review
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveThough depression often afflicts head and neck cancer (HNC) patients, few studies have examined the association between depression and survival in this particular cancer population. The objective of this study is to investigate the five-year survival of HNC patients by depression status. MATERIALS AND
methodsThis study used SEER-Medicare data from 2002-2010 and identified depression diagnosis two years before and one year after cancer diagnosis. HNC patients were identified using ICD-O3 codes and depression was identified using ICD-9-CM codes from Medicare claims.
resultsOf the 3466 patients included in the study, 642 (18.5%) were diagnosed with depression during the study period. Compared to those who received no depression diagnosis, those diagnosed with depression prior to cancer or after cancer diagnosis were more likely to die of cancer (HR=1.49; 95% CI=1.27, 1.76 and HR=1.38; 95% CI=1.16, 1.65, respectively). Similarly, when looking at death from any cause, those diagnosed with depression prior to cancer diagnosis and those who received a diagnosis of depression after cancer were more likely to die from any death compared to those without depression (HR=1.55; 95% CI=1.36, 1.76 and HR=1.40; 95% CI=1.21, 1.62, respectively).
conclusionsThe results emphasize the need for early identification and treatment of depression in HNC patients, as well as the establishment of policies to routinely screen these patients throughout the cancer treatment process.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.