Evidence map›Paper›PMID 28109014›Full record

ReviewDevelopmental dynamics : an official publication of the American Association of Anatomists2017

Urothelial generation and regeneration in development, injury, and cancer.

Caihong Wang, Whitney Trotter Ross, Indira U Mysorekar

Open access · greenAbstract readReview
In one paragraph

Review in Developmental dynamics : an official publication of the American Association of Anatomists, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 60 citations in OpenAlex.

  1. Article
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  9. Review
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  15. Review
  16. Article
  17. Article
  18. Urothelial progenitors in development and repair.Pediatric nephrology (Berlin, Germany) · 2022
    Review
  19. Article
  20. Piezo channels in the urinary system.Experimental & molecular medicine · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Caihong WangDepartment of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri.
Whitney Trotter RossDepartment of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri.
Indira U MysorekarDepartment of Obstetrics and Gynecology, Washington University School of Medicine, St. Louis, Missouri.
Washington University in St. Louis · US

Funding

Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
ATG16L1 AND MOLECULAR REGULATION OF BACTERIAL PERSISTENCER01DK100644 · NIDDK · WASHINGTON UNIVERSITY · PI MYSOREKAR, INDIRA U · 2013 to 2017
$1.7M
INTERLEUKIN-6 AND AGING: IMPACT ON IMMUNE DEFENSE AND TISSUE REPAIR IN URINARY BLADDERR01AG052494 · NIA · WASHINGTON UNIVERSITY · PI LOWDER, JERRY LANE, MYSOREKAR, INDIRA U · 2016 to 2020
$1.6M
NCATS NIH HHS UL1 TR000448NIA NIH HHS R01 AG052494NIA NIH HHS R56 AG052494NIDDK NIH HHS R01 DK100644
6 · The paper itself

Abstract

Homeostatic maintenance and repair of the urothelium upon injury are required for a functional bladder in both healthy and disease conditions. Understanding the cellular and molecular mechanisms underlying the urothelial regenerative response is key to designing strategies for tissue repair and ultimately treatments for urologic diseases including urinary tract infections, voiding dysfunction, painful bladder syndrome, and bladder cancer. In this article, we review studies on urothelial ontogeny during development and regeneration following various injury modalities. Signaling pathways involved in urothelial regeneration and in urothelial carcinogenesis are also discussed. Developmental Dynamics 246:336-343, 2017. © 2016 Wiley Periodicals, Inc.

Indexed as

RegenerationAnimalsHumansSignal TransductionUrinary BladderUrologic DiseasesUrologic NeoplasmsUrotheliumbladderprogenitor cellsregenerationstem cellsUropathogenic E. coli; urinary tract infections; retinoic acid; BMP4

Identifiers

PMID28109014
PMCPMC5354960
OpenAlexW2571743364

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.