Evidence map›Paper›PMID 28108895›Full record

ReviewAdvances in therapy2017

Chronic Wound Healing: A Review of Current Management and Treatments.

George Han, Roger Ceilley

Registry-linked trialAbstract readReview
In one paragraph

Review in Advances in therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05046158 (Randomized Clinical Trial to Compare Transforming Powder and Standard of Care Dressing Therapies to Heal Diabetic Foot Ulcers), which is not on this map. Cited by 758 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
758citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05046158 nacompletednot on this mapstarted 2021, after this paper: background citation

Randomized Clinical Trial to Compare Transforming Powder and Standard of Care Dressing Therapies to Heal Diabetic Foot Ulcers

TypeinterventionalSponsorULURU Inc.Ran2021 to 2025Enrolled135ConditionsDiabetic Foot UlcerArmsTransforming Powder Dressing, Standard of care topical wound agents and dressings
3 · Its place in the literature

Who cites it

758 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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698 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

George HanIcahn School of Medicine at Mount Sinai, New York, NY, USA. george.han@mountsinai.org.ORCID 0000-0003-3302-5098
Roger CeilleyUniversity of Iowa, Iowa City, IA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wound healing is a complex, highly regulated process that is critical in maintaining the barrier function of skin. With numerous disease processes, the cascade of events involved in wound healing can be affected, resulting in chronic, non-healing wounds that subject the patient to significant discomfort and distress while draining the medical system of an enormous amount of resources. The healing of a superficial wound requires many factors to work in concert, and wound dressings and treatments have evolved considerably to address possible barriers to wound healing, ranging from infection to hypoxia. Even optimally, wound tissue never reaches its pre-injured strength and multiple aberrant healing states can result in chronic non-healing wounds. This article will review wound healing physiology and discuss current approaches for treating a wound.

Indexed as

Skin UlcerChronic DiseaseHumansPatient Care ManagementWound HealingBiofilmsChronic woundsGrowth factorsHyperbaric oxygenNegative pressure wound therapySkin infectionSkin substitutesWound dressingsWound healing

Identifiers

PMID28108895
PMCPMC5350204

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.