Evidence map›Paper›PMID 28108814›Full record

ArticleEuropean biophysics journal : EBJ2017

The small neurotoxin apamin blocks not only small conductance Ca

Patrick Voos, Mehtap Yazar, René Lautenschläger, Oliver Rauh, Anna Moroni, Gerhard Thiel

Abstract read
PubMed Publisher
In one paragraph

Article in European biophysics journal : EBJ, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Atrial arrhythmogenesis and electrophysiological remodeling in hypokalaemic metabolic syndrome: the role of apamin-sensitive SK channels.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
  2. Article
  3. Apamin structure and pharmacology revisited.Frontiers in pharmacology · 2022
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Small-conductance CaExperimental & molecular medicine · 2018
    Review
  10. KFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2018
    Article
  11. Article
  12. Dynamic coupling between TRPV4 and CaAmerican journal of physiology. Renal physiology · 2017
    Article
  13. Pharmacological blockade of small conductance CaPflugers Archiv : European journal of physiology · 2017
    Article
  14. Prefrontal Cortex KThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Patrick VoosDepartment of Biology, Plant Membrane Biophysics, Technische Universität Darmstadt, Schnittspahnstrasse 3, 64287, Darmstadt, Germany.
Mehtap YazarDepartment of Biology, Plant Membrane Biophysics, Technische Universität Darmstadt, Schnittspahnstrasse 3, 64287, Darmstadt, Germany.
René LautenschlägerDepartment of Biology, Plant Membrane Biophysics, Technische Universität Darmstadt, Schnittspahnstrasse 3, 64287, Darmstadt, Germany.
Oliver RauhDepartment of Biology, Plant Membrane Biophysics, Technische Universität Darmstadt, Schnittspahnstrasse 3, 64287, Darmstadt, Germany.
Anna MoroniDepartment of Biology and CNR IBF-Mi, Università degli Studi di Milano, Milan, Italy.
Gerhard ThielDepartment of Biology, Plant Membrane Biophysics, Technische Universität Darmstadt, Schnittspahnstrasse 3, 64287, Darmstadt, Germany. thiel@bio.tu-darmstadt.de.
Technical University of Darmstadt · DEUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Apamin is frequently used as a specific blocker of small-conductance Ca

Indexed as

ApaminElectrophysiological PhenomenaHEK293 CellsHumansInhibitory Concentration 50Kv1.3 Potassium ChannelNeurotoxinsPancreatitis-Associated ProteinsPotassium Channel BlockersPotassium Channels, Calcium-ActivatedApaminKv1.3 Potassium ChannelNeurotoxinsPancreatitis-Associated ProteinsPotassium Channel BlockersPotassium Channels, Calcium-ActivatedREG3A protein, humanApamin blockJurkatKv1.3 channelLymphocytesSK channel

Identifiers

PMID28108814
OpenAlexW2574994845

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.