ArticleEuropean journal of clinical pharmacology2017
Potentially inappropriate medications: predictor for mortality in a cohort of community-dwelling older adults.
Article in European journal of clinical pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Beneficial outcomes of medication review in patients with hip fractures: a systematic review.European geriatric medicine · 2025Pooled it
- A Prospective Study on Potentially Inappropriate Drug Use and All-Cause Mortality in Community-Dwelling Older Adults.Journal of the American Geriatrics Society · 2025Article
- Potentially inappropriate medication use is associated with increased risk of incident disability in healthy older adults.Journal of the American Geriatrics Society · 2023Article
- Clinical pharmacist intervention to improve medication safety for hip fracture patients through secondary and primary care settings: a nonrandomised controlled trial.Journal of orthopaedic surgery and research · 2023Article
- Overuse of medications in low- and middle-income countries: a scoping review.Bulletin of the World Health Organization · 2023Article
- Review
- Risk factors for potentially inappropriate medication use in older adults: a cohort study.International journal of clinical pharmacy · 2022Article
- Assessment of Potentially Inappropriate Medications Using the EU (7)-PIM List, in a Sample of Portuguese Older Adults' Residents in Nursing Homes.Risk management and healthcare policy · 2022Article
- The impact of decreasing potentially inappropriate medications on activities of daily living in a convalescent rehabilitation setting.International journal of clinical pharmacy · 2021Observational
- A multidimensional measure of polypharmacy for older adults using the Health and Retirement Study.Scientific reports · 2021Article
- Based on the Beers Criteria 2019 Edition Over-the-Counter Drugs Risk Confirmation of Elderly Chinese.BioMed research international · 2021Article
- Hypertension and Drug Adherence in the Elderly.Frontiers in cardiovascular medicine · 2020Review
- Potentially inappropriate medications for the elderly: Incidence and impact on mortality in a cohort ten-year follow-up.PloS one · 2020Article
- The association of potentially inappropriate medication use on health outcomes and hospital costs in community-dwelling older persons: a longitudinal 12-year study.The European journal of health economics : HEPAC : health economics in prevention and care · 2019Article
- Pain and Inflammation Management in Older Adults: A Brazilian Consensus of Potentially Inappropriate Medication and Their Alternative Therapies.Frontiers in pharmacology · 2019Article
- Potentially inappropriate medication in palliative care patients according to STOPP-Frail criteria.European geriatric medicine · 2018Article
- American Geriatrics Society-Beers Criteria and adverse drug reactions: a comparative cross-sectional study of Nigerian and South African older inpatients.Clinical interventions in aging · 2018Article
- Polypharmacy leads to increased prevalence of potentially inappropriate medication in the Indonesian geriatric population visiting primary care facilities.Therapeutics and clinical risk management · 2018Article
- Potentially inappropriate medications at admission among elderly patients transported to a tertiary emergency medical institution in Japan.Acute medicine & surgeryArticle
- Potentially inappropriate medications at discharge among elderly patients at a single tertiary emergency medical institution in Japan: a retrospective cross-sectional observational study.Acute medicine & surgeryArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe objective of this study was to investigate whether the potentially inappropriate medication (PIM) use is a predictor for mortality in a community-based population of older adults.
methodsA cohort study was performed between January 1, 1997, and December 31, 2011, based on data from a representative sample of the population aged 60 years or older living in Bambuí, Brazil. Univariate and multivariate analyses of the association between the variable of interest (use of PIM or pharmacological groups of PIM) and mortality were based on the extended Cox model for proportional hazards. The extended model was adopted to include the measurement of the exposure of interest throughout the follow-up period and not only at baseline. Adjustment variables included sociodemographic characteristics, health status, and use of health care services and medications. A level of significance of 5% was adopted for all analyses.
resultsThe prevalence of PIM use was 56.0% (95%CI 53.4-58.6). After multiple adjustments, the risk of death among users of at least one PIM was 44% higher (HR = 1.44; 95%CI 1.21 to 1.71) than among those who did not use any PIM. Among the PIM groups analyzed, antipsychotics were the most strongly associated with mortality (HR = 2.33; 95%CI 1.72 to 3.17).
conclusionsThe study revealed a high prevalence of PIM use among the community-based aged population. It also identified PIM use as a predictor for mortality in this group of individuals. This indicates the need for selection of safer drug therapy alternatives in this patient group.
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