Evidence map›Paper›PMID 28108647›Full record

ArticlePhysiological reports2017

Effects of early-life exposure to THIP on brainstem neuronal excitability in the Mecp2-null mouse model of Rett syndrome before and after drug withdrawal.

Weiwei Zhong, Christopher M Johnson, Ningren Cui, Max F Oginsky, Yang Wu, Chun Jiang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiological reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. GABAergic System Dysfunction in Autism Spectrum Disorders.Frontiers in cell and developmental biology · 2021
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Weiwei ZhongDepartment of Biology, Georgia State University, Atlanta, Georgia.
Christopher M JohnsonDepartment of Biology, Georgia State University, Atlanta, Georgia.
Ningren CuiDepartment of Biology, Georgia State University, Atlanta, Georgia.
Max F OginskyDepartment of Biology, Georgia State University, Atlanta, Georgia.
Yang WuDepartment of Biology, Georgia State University, Atlanta, Georgia.
Chun JiangDepartment of Biology, Georgia State University, Atlanta, Georgia cjiang@gsu.edu.
Georgia State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rett syndrome (RTT) is mostly caused by mutations of the X-linked MECP2 gene. Although the causal neuronal mechanisms are still unclear, accumulating experimental evidence obtained from Mecp2

Indexed as

Action PotentialsAnimalsApneaDisease Models, AnimalFemaleGABA-A Receptor AgonistsIsoxazolesLocus CoeruleusMaleMethyl-CpG-Binding Protein 2MiceMice, Inbred C57BLMice, TransgenicNeuronsReceptors, GABA-ARett SyndromeGABA-A Receptor AgonistsgaboxadolIsoxazolesMecp2 protein, mouseMethyl-CpG-Binding Protein 2Receptors, GABA-AElectrophysiologygaboxadollocus coeruleusMecp2mesencephalic trigeminalneuronal hyperexcitability

Identifiers

PMID28108647
PMCPMC5269412
OpenAlexW2574397419

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.