ArticleGenetics2017
Fluctuating Selection in the Moran.
Article in Genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed.
- Article
- Tackling the Pangenome Dilemma Requires the Concerted Analysis of Multiple Population Genetic Processes.Genome biology and evolution · 2023Article
- The role of evolutionary game theory in spatial and non-spatial models of the survival of cooperation in cancer: a review.Journal of the Royal Society, Interface · 2022Review
- Strong selective environments determine evolutionary outcome in time-dependent fitness seascapes.Evolution letters · 2022Article
- How the storage effect and the number of temporal niches affect biodiversity in stochastic and seasonal environments.PLoS computational biology · 2022Article
- Article
- Signals of selection in the mitogenome provide insights into adaptation mechanisms in heterogeneous habitats in a widely distributed pelagic fish.Scientific reports · 2020Article
- Noise-induced stabilization and fixation in fluctuating environment.Scientific reports · 2018Article
- Seasonally fluctuating selection can maintain polymorphism at many loci via segregation lift.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Genotype by random environmental interactions gives an advantage to non-favored minor alleles.Scientific reports · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Contrary to classical population genetics theory, experiments demonstrate that fluctuating selection can protect a haploid polymorphism in the absence of frequency dependent effects on fitness. Using forward simulations with the Moran model, we confirm our analytical results showing that a fluctuating selection regime, with a mean selection coefficient of zero, promotes polymorphism. We find that increases in heterozygosity over neutral expectations are especially pronounced when fluctuations are rapid, mutation is weak, the population size is large, and the variance in selection is big. Lowering the frequency of fluctuations makes selection more directional, and so heterozygosity declines. We also show that fluctuating selection raises
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.