Evidence map›Paper›PMID 28108511›Full record

ArticleCancer research2017

Biomarker-Based PET Imaging of Diffuse Intrinsic Pontine Glioma in Mouse Models.

Susanne Kossatz, Brandon Carney, Melanie Schweitzer, Giuseppe Carlucci, Vesselin Z Miloushev, Uday B Maachani, Prajwal Rajappa, Kayvan R Keshari, David Pisapia, Wolfgang A Weber and 2 more

Abstract read
In one paragraph

Article in Cancer research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 30 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Targeted Brain Tumor Radiotherapy Using an Auger Emitter.Clinical cancer research : an official journal of the American Association for Cancer Research · 2020
    Article
  10. Article
  11. Approaches to PET Imaging of Glioblastoma.Molecules (Basel, Switzerland) · 2020
    Review
  12. Review
  13. Article
  14. PARP-1-Targeted Radiotherapy in Mouse Models of Glioblastoma.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2018
    Article
  15. Article
  16. Targeted PET imaging strategy to differentiate malignant from inflamed lymph nodes in diffuse large B-cell lymphoma.Proceedings of the National Academy of Sciences of the United States of America · 2017
    Article
  17. Article
  18. Molecular Imaging of PARP.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2017
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Susanne KossatzDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Brandon CarneyDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Melanie SchweitzerDepartment of Neurological Surgery, Weill Cornell Medical College, New York, New York.
Giuseppe CarlucciDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Vesselin Z MiloushevDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Uday B MaachaniDepartment of Neurological Surgery, Weill Cornell Medical College, New York, New York.
Prajwal RajappaDepartment of Neurological Surgery, Weill Cornell Medical College, New York, New York.
Kayvan R KeshariDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
David PisapiaDepartment of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, New York.
Wolfgang A WeberDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.
Mark M SouweidaneDepartment of Neurological Surgery, Weill Cornell Medical College, New York, New York.
Thomas ReinerDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York. reinert@mskcc.org.
Memorial Sloan Kettering Cancer Center · USCornell University · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Radioiodinated Multifunctional PARP1 Imaging Probes for Diagnosis and TherapyR01CA204441 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI PILLARSETTY, NAGAVARAKISHORE · 2016 to 2020
$2.9M
PET/MRI to study nanotherapy in atherosclerosisR01HL125703 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MULDER, WILLEM · 2015 to 2018
$2.4M
Bioorthogonal Strategies for Targeted PET Imaging Probe DevelopmentK25EB016673 · NIBIB · SLOAN-KETTERING INST CAN RESEARCH · PI REINER, THOMAS · 2013 to 2015
$525k
Development of Nuclear Auger Emitters for Targeted RadiotherapyR21CA191679 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI REINER, THOMAS, WEBER, WOLFGANG · 2015 to 2016
$187k
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA204441NCI NIH HHS R21 CA191679NHLBI NIH HHS R01 HL125703NIBIB NIH HHS K25 EB016673
6 · The paper itself

Abstract

Diffuse intrinsic pontine glioma (DIPG) is a childhood brainstem tumor with a universally poor prognosis. Here, we characterize a positron emission tomography (PET) probe for imaging DIPG

Indexed as

AnimalsBiomarkers, TumorBrain Stem NeoplasmsChickensDisease Models, AnimalFormaldehydeGliomaHumansMagnetic Resonance ImagingMiceParaffin EmbeddingPoly (ADP-Ribose) Polymerase-1Positron-Emission TomographyPositron Emission Tomography Computed TomographyRadiopharmaceuticalsTissue FixationBiomarkers, TumorFormaldehydePARP1 protein, humanPoly (ADP-Ribose) Polymerase-1Radiopharmaceuticals

Identifiers

PMID28108511
PMCPMC5392368
OpenAlexW2578173341

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.