ArticleNeuroscience2017
Dcc haploinsufficiency regulates dopamine receptor expression across postnatal lifespan.
Article in Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 14 citations in OpenAlex.
- Changes in social reward across adolescence in male mice.Scientific reports · 2025Article
- Sex differences in membrane properties and cellular excitability of dopamine D1 receptor-expressing neurons within the shell of the nucleus accumbens of pre- and mid-adolescent mice.Biology of sex differences · 2024Article
- Sexually dimorphic characteristics of dopamine D1 receptor-expressing neurons within the shell of the nucleus accumbens of adolescent mice.Research square · 2023Article
- Neural plasticity and depression treatment.IBRO neuroscience reports · 2023Article
- Coming of age in the frontal cortex: The role of puberty in cortical maturation.Seminars in cell & developmental biology · 2021Review
- Review
- Mesocorticolimbic Dopamine Pathways Across Adolescence: Diversity in Development.Frontiers in neural circuits · 2021Review
- Early Adolescence is a Critical Period for the Maturation of Inhibitory Behavior.Cerebral cortex (New York, N.Y. : 1991) · 2019Article
- Making Dopamine Connections in Adolescence.Trends in neurosciences · 2017Review
- Adolescence and Reward: Making Sense of Neural and Behavioral Changes Amid the Chaos.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Adolescence is a period during which the medial prefrontal cortex (mPFC) undergoes significant remodeling. The netrin-1 receptor, deleted in colorectal cancer (DCC), controls the extent and organization of mPFC dopamine connectivity during adolescence and in turn directs mPFC functional and structural maturation. Dcc haploinsufficiency leads to increased mPFC dopamine input, which causes improved cognitive processing and resilience to behavioral effects of stimulant drugs of abuse. Here we examine the effects of Dcc haploinsufficiency on the dynamic expression of dopamine receptors in forebrain targets of C57BL6 mice. We conducted quantitative receptor autoradiography experiments with [
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.